In silico evaluation of DNA Damage Inducible Transcript 4 gene (DDIT4) as prognostic biomarker in several malignancies

In silico evaluation of DNA Damage Inducible Transcript 4 gene (DDIT4) as prognostic biomarker in several malignancies

Abstract DDIT4 gene encodes a protein whose main action is to inhibit mTOR under stress conditions whilst several in vitro studies indicate that its expression favors cancer progression. We have previously described that DDIT4 expression is an independent prognostic factor for tripe negative breast...

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Autores principales: Joseph A. Pinto, Christian Rolfo, Luis E. Raez, Alexandra Prado, Jhajaira M. Araujo, Leny Bravo, Williams Fajardo, Zaida D. Morante, Alfredo Aguilar, Silvia P. Neciosup, Luis A. Mas, Denisse Bretel, Justin M. Balko, Henry L. Gomez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/ccc0b31bd651450f8f9b7c7df4a29318
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