Independent regulation of age associated fat accumulation and longevity

Age-associated metabolic changes include lipid accumulation. Here, the authors show that with replicative aging yeast accumulate lipid droplets which protect cells from cold stress and can be modulated through Biosynthesis of NAD+ 2 (BNA2).

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Detalles Bibliográficos
Autores principales: Anthony O. Beas, Patricia B. Gordon, Clara L. Prentiss, Carissa Perez Olsen, Matthew A. Kukurugya, Bryson D. Bennett, Susan M. Parkhurst, Daniel E. Gottschling
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ccc42411f0664158949caf4ea685050d
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Sumario:Age-associated metabolic changes include lipid accumulation. Here, the authors show that with replicative aging yeast accumulate lipid droplets which protect cells from cold stress and can be modulated through Biosynthesis of NAD+ 2 (BNA2).