Independent regulation of age associated fat accumulation and longevity

Age-associated metabolic changes include lipid accumulation. Here, the authors show that with replicative aging yeast accumulate lipid droplets which protect cells from cold stress and can be modulated through Biosynthesis of NAD+ 2 (BNA2).

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Detalles Bibliográficos
Autores principales:	Anthony O. Beas, Patricia B. Gordon, Clara L. Prentiss, Carissa Perez Olsen, Matthew A. Kukurugya, Bryson D. Bennett, Susan M. Parkhurst, Daniel E. Gottschling
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ccc42411f0664158949caf4ea685050d
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spelling	oai:doaj.org-article:ccc42411f0664158949caf4ea685050d2021-12-02T15:03:03ZIndependent regulation of age associated fat accumulation and longevity10.1038/s41467-020-16358-72041-1723https://doaj.org/article/ccc42411f0664158949caf4ea685050d2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16358-7https://doaj.org/toc/2041-1723Age-associated metabolic changes include lipid accumulation. Here, the authors show that with replicative aging yeast accumulate lipid droplets which protect cells from cold stress and can be modulated through Biosynthesis of NAD+ 2 (BNA2).Anthony O. BeasPatricia B. GordonClara L. PrentissCarissa Perez OlsenMatthew A. KukurugyaBryson D. BennettSusan M. ParkhurstDaniel E. GottschlingNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anthony O. Beas Patricia B. Gordon Clara L. Prentiss Carissa Perez Olsen Matthew A. Kukurugya Bryson D. Bennett Susan M. Parkhurst Daniel E. Gottschling Independent regulation of age associated fat accumulation and longevity
description	Age-associated metabolic changes include lipid accumulation. Here, the authors show that with replicative aging yeast accumulate lipid droplets which protect cells from cold stress and can be modulated through Biosynthesis of NAD+ 2 (BNA2).
format	article
author	Anthony O. Beas Patricia B. Gordon Clara L. Prentiss Carissa Perez Olsen Matthew A. Kukurugya Bryson D. Bennett Susan M. Parkhurst Daniel E. Gottschling
author_facet	Anthony O. Beas Patricia B. Gordon Clara L. Prentiss Carissa Perez Olsen Matthew A. Kukurugya Bryson D. Bennett Susan M. Parkhurst Daniel E. Gottschling
author_sort	Anthony O. Beas
title	Independent regulation of age associated fat accumulation and longevity
title_short	Independent regulation of age associated fat accumulation and longevity
title_full	Independent regulation of age associated fat accumulation and longevity
title_fullStr	Independent regulation of age associated fat accumulation and longevity
title_full_unstemmed	Independent regulation of age associated fat accumulation and longevity
title_sort	independent regulation of age associated fat accumulation and longevity
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/ccc42411f0664158949caf4ea685050d
work_keys_str_mv	AT anthonyobeas independentregulationofageassociatedfataccumulationandlongevity AT patriciabgordon independentregulationofageassociatedfataccumulationandlongevity AT claralprentiss independentregulationofageassociatedfataccumulationandlongevity AT carissaperezolsen independentregulationofageassociatedfataccumulationandlongevity AT matthewakukurugya independentregulationofageassociatedfataccumulationandlongevity AT brysondbennett independentregulationofageassociatedfataccumulationandlongevity AT susanmparkhurst independentregulationofageassociatedfataccumulationandlongevity AT danielegottschling independentregulationofageassociatedfataccumulationandlongevity
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Independent regulation of age associated fat accumulation and longevity

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