Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time
Abstract Accumulation of progerin is believed to underlie the pathophysiology of Hutchinson-Gilford progeria syndrome, a disease characterized by clinical features suggestive of premature aging, including loss of subcutaneous white adipose tissue (sWAT). Although progerin has been found in cells and...
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Autores principales: | Gwladys Revêchon, Nikenza Viceconte, Tomás McKenna, Agustín Sola Carvajal, Peter Vrtačnik, Peter Stenvinkel, Torbjörn Lundgren, Kjell Hultenby, Irene Franco, Maria Eriksson |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/ccc79d39571149198d742b1696417602 |
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