When metabolic prowess is too much of a good thing: how carbon catabolite repression and metabolic versatility impede production of esterified α,ω-diols in Pseudomonas putida KT2440

Abstract Background Medium-chain-length α,ω-diols (mcl-diols) are important building blocks in polymer production. Recently, microbial mcl-diol production from alkanes was achieved in E. coli (albeit at low rates) using the alkane monooxygenase system AlkBGTL and esterification module Atf1. Owing to...

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Auteurs principaux:	Chunzhe Lu, Christos Batianis, Edward Ofori Akwafo, Rene H. Wijffels, Vitor A. P. Martins dos Santos, Ruud A. Weusthuis
Format:	article
Langue:	EN
Publié:	BMC 2021
Sujets:	Metabolic versatility Substrate preference Monooxygenase Medium-chain-length α,ω-diols ω-Oxyfunctionalization Pseudomonas putida Fuel TP315-360 Biotechnology TP248.13-248.65
Accès en ligne:	https://doaj.org/article/cccab6659f2b4e9f97c37ef1498f1577
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When metabolic prowess is too much of a good thing: how carbon catabolite repression and metabolic versatility impede production of esterified α,ω-diols in Pseudomonas putida KT2440

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