A cell-based computational model of early embryogenesis coupling mechanical behaviour and gene regulation

Embryonic development is a complex process where genetic and biochemical information direct morphogenesis. Here the authors describe MecaGen, an agent-based model and simulation platform of multicellular development designed to allow a quantitative comparison between simulations and real biological...

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Autores principales: Julien Delile, Matthieu Herrmann, Nadine Peyriéras, René Doursat
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/cccbae085a244c23941a41eb597b8505
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spelling oai:doaj.org-article:cccbae085a244c23941a41eb597b85052021-12-02T14:40:57ZA cell-based computational model of early embryogenesis coupling mechanical behaviour and gene regulation10.1038/ncomms139292041-1723https://doaj.org/article/cccbae085a244c23941a41eb597b85052017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms13929https://doaj.org/toc/2041-1723Embryonic development is a complex process where genetic and biochemical information direct morphogenesis. Here the authors describe MecaGen, an agent-based model and simulation platform of multicellular development designed to allow a quantitative comparison between simulations and real biological data.Julien DelileMatthieu HerrmannNadine PeyriérasRené DoursatNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Julien Delile
Matthieu Herrmann
Nadine Peyriéras
René Doursat
A cell-based computational model of early embryogenesis coupling mechanical behaviour and gene regulation
description Embryonic development is a complex process where genetic and biochemical information direct morphogenesis. Here the authors describe MecaGen, an agent-based model and simulation platform of multicellular development designed to allow a quantitative comparison between simulations and real biological data.
format article
author Julien Delile
Matthieu Herrmann
Nadine Peyriéras
René Doursat
author_facet Julien Delile
Matthieu Herrmann
Nadine Peyriéras
René Doursat
author_sort Julien Delile
title A cell-based computational model of early embryogenesis coupling mechanical behaviour and gene regulation
title_short A cell-based computational model of early embryogenesis coupling mechanical behaviour and gene regulation
title_full A cell-based computational model of early embryogenesis coupling mechanical behaviour and gene regulation
title_fullStr A cell-based computational model of early embryogenesis coupling mechanical behaviour and gene regulation
title_full_unstemmed A cell-based computational model of early embryogenesis coupling mechanical behaviour and gene regulation
title_sort cell-based computational model of early embryogenesis coupling mechanical behaviour and gene regulation
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/cccbae085a244c23941a41eb597b8505
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