Non-Enzymatic Amperometric Glucose Screen-Printed Sensors Based on Copper and Copper Oxide Particles

Non-enzymatic amperometric glucose sensors have gained much attention in the past decade because of the better chemical and thermal stability and biocompatibility compared to conventional sensors based on the use of biomolecules. This study focuses on a novel copper and copper oxide-based glucose se...

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Autores principales: Carlota Guati, Lucía Gomez-Coma, Marcos Fallanza, Inmaculada Ortiz
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Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:ccd7d5bdf72948c7ad671c874023d81c2021-11-25T16:39:10ZNon-Enzymatic Amperometric Glucose Screen-Printed Sensors Based on Copper and Copper Oxide Particles10.3390/app1122108302076-3417https://doaj.org/article/ccd7d5bdf72948c7ad671c874023d81c2021-11-01T00:00:00Zhttps://www.mdpi.com/2076-3417/11/22/10830https://doaj.org/toc/2076-3417Non-enzymatic amperometric glucose sensors have gained much attention in the past decade because of the better chemical and thermal stability and biocompatibility compared to conventional sensors based on the use of biomolecules. This study focuses on a novel copper and copper oxide-based glucose sensor synthesized by an electrodeposition technique through a rigorous protocol which reports an excellent analytical performance due to its structure and its increased active area. In addition, the linear response range, detection limit and sensitivity were 0.5–5.0 mmol L<sup>−1</sup>, 0.002 mmol L<sup>−1</sup>, 904 μA mmol<sup>−1</sup> L<sup>−1</sup> cm<sup>−2</sup>, respectively. Results show a reliable electrode as it is chemically stable, exhibits rapid and excellent sensitivity, and it is not significantly affected by coexisting species present in the blood samples; furthermore, it reports a maximum relative standard deviation error (RSD) of 6%, and showed long operating life as the electrode was used for thousand measurements of 4.0 mmol L<sup>−1</sup> glucose solution during three days.Carlota GuatiLucía Gomez-ComaMarcos FallanzaInmaculada OrtizMDPI AGarticleglucose sensornon-enzymaticcopper oxidesensitivityTechnologyTEngineering (General). Civil engineering (General)TA1-2040Biology (General)QH301-705.5PhysicsQC1-999ChemistryQD1-999ENApplied Sciences, Vol 11, Iss 10830, p 10830 (2021)
institution DOAJ
collection DOAJ
language EN
topic glucose sensor
non-enzymatic
copper oxide
sensitivity
Technology
T
Engineering (General). Civil engineering (General)
TA1-2040
Biology (General)
QH301-705.5
Physics
QC1-999
Chemistry
QD1-999
spellingShingle glucose sensor
non-enzymatic
copper oxide
sensitivity
Technology
T
Engineering (General). Civil engineering (General)
TA1-2040
Biology (General)
QH301-705.5
Physics
QC1-999
Chemistry
QD1-999
Carlota Guati
Lucía Gomez-Coma
Marcos Fallanza
Inmaculada Ortiz
Non-Enzymatic Amperometric Glucose Screen-Printed Sensors Based on Copper and Copper Oxide Particles
description Non-enzymatic amperometric glucose sensors have gained much attention in the past decade because of the better chemical and thermal stability and biocompatibility compared to conventional sensors based on the use of biomolecules. This study focuses on a novel copper and copper oxide-based glucose sensor synthesized by an electrodeposition technique through a rigorous protocol which reports an excellent analytical performance due to its structure and its increased active area. In addition, the linear response range, detection limit and sensitivity were 0.5–5.0 mmol L<sup>−1</sup>, 0.002 mmol L<sup>−1</sup>, 904 μA mmol<sup>−1</sup> L<sup>−1</sup> cm<sup>−2</sup>, respectively. Results show a reliable electrode as it is chemically stable, exhibits rapid and excellent sensitivity, and it is not significantly affected by coexisting species present in the blood samples; furthermore, it reports a maximum relative standard deviation error (RSD) of 6%, and showed long operating life as the electrode was used for thousand measurements of 4.0 mmol L<sup>−1</sup> glucose solution during three days.
format article
author Carlota Guati
Lucía Gomez-Coma
Marcos Fallanza
Inmaculada Ortiz
author_facet Carlota Guati
Lucía Gomez-Coma
Marcos Fallanza
Inmaculada Ortiz
author_sort Carlota Guati
title Non-Enzymatic Amperometric Glucose Screen-Printed Sensors Based on Copper and Copper Oxide Particles
title_short Non-Enzymatic Amperometric Glucose Screen-Printed Sensors Based on Copper and Copper Oxide Particles
title_full Non-Enzymatic Amperometric Glucose Screen-Printed Sensors Based on Copper and Copper Oxide Particles
title_fullStr Non-Enzymatic Amperometric Glucose Screen-Printed Sensors Based on Copper and Copper Oxide Particles
title_full_unstemmed Non-Enzymatic Amperometric Glucose Screen-Printed Sensors Based on Copper and Copper Oxide Particles
title_sort non-enzymatic amperometric glucose screen-printed sensors based on copper and copper oxide particles
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/ccd7d5bdf72948c7ad671c874023d81c
work_keys_str_mv AT carlotaguati nonenzymaticamperometricglucosescreenprintedsensorsbasedoncopperandcopperoxideparticles
AT luciagomezcoma nonenzymaticamperometricglucosescreenprintedsensorsbasedoncopperandcopperoxideparticles
AT marcosfallanza nonenzymaticamperometricglucosescreenprintedsensorsbasedoncopperandcopperoxideparticles
AT inmaculadaortiz nonenzymaticamperometricglucosescreenprintedsensorsbasedoncopperandcopperoxideparticles
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