Two diagnoses become one? Rare case report of anorexia nervosa and Cushing’s syndrome

Nadia Sawicka,* Maria Gryczyńska,* Jerzy Sowiński, Monika Tamborska-Zedlewska, Marek Ruchała Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland*These authors contributed equally to this workAbstract: Hypothalamic-pituitary-adrenal axi...

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Autores principales: Sawicka N, Gryczyńska M, Sowiński J, Tamborska-Zedlewska M, Ruchała M
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Publicado: Dove Medical Press 2013
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spelling oai:doaj.org-article:ccdcd68402d64dbc9412752d475971bf2021-12-02T06:34:16ZTwo diagnoses become one? Rare case report of anorexia nervosa and Cushing’s syndrome1176-63281178-2021https://doaj.org/article/ccdcd68402d64dbc9412752d475971bf2013-03-01T00:00:00Zhttp://www.dovepress.com/two-diagnoses-become-one-rare-case-report-of-anorexia-nervosa-and-cush-a12626https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Nadia Sawicka,* Maria Gryczyńska,* Jerzy Sowiński, Monika Tamborska-Zedlewska, Marek Ruchała Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland*These authors contributed equally to this workAbstract: Hypothalamic-pituitary-adrenal axis impairment in anorexia nervosa is marked by hypercortisolemia, and psychiatric disorders occur in the majority of patients with Cushing’s syndrome. Here we report a patient diagnosed with anorexia nervosa who also developed Cushing’s syndrome. A 26-year-old female had been treated for anorexia nervosa since she was 17 years old, and also developed depression and paranoid schizophrenia. She was admitted to the Department of Endocrinology, Metabolism, and Internal Medicine with a preliminary diagnosis of Cushing’s syndrome. Computed tomography revealed a 27 mm left adrenal tumor, and she underwent laparoscopic adrenalectomy. She was admitted to hospital 6 months after this procedure, at which time she did not report any eating or mood disorder. This is a rare case report of a patient with anorexia nervosa in whom Cushing’s syndrome was subsequently diagnosed. Diagnostic difficulties were caused by the signs and symptoms presenting in the course of both disorders, ie, hypercortisolemia, osteoporosis, secondary amenorrhea, striae, hypokalemia, muscle weakness, and depression.Keywords: anorexia nervosa, Cushing’s syndrome, adrenalectomy, osteoporosisSawicka NGryczyńska MSowiński JTamborska-Zedlewska MRuchała MDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2013, Iss default, Pp 431-435 (2013)
institution DOAJ
collection DOAJ
language EN
topic Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Sawicka N
Gryczyńska M
Sowiński J
Tamborska-Zedlewska M
Ruchała M
Two diagnoses become one? Rare case report of anorexia nervosa and Cushing’s syndrome
description Nadia Sawicka,* Maria Gryczyńska,* Jerzy Sowiński, Monika Tamborska-Zedlewska, Marek Ruchała Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland*These authors contributed equally to this workAbstract: Hypothalamic-pituitary-adrenal axis impairment in anorexia nervosa is marked by hypercortisolemia, and psychiatric disorders occur in the majority of patients with Cushing’s syndrome. Here we report a patient diagnosed with anorexia nervosa who also developed Cushing’s syndrome. A 26-year-old female had been treated for anorexia nervosa since she was 17 years old, and also developed depression and paranoid schizophrenia. She was admitted to the Department of Endocrinology, Metabolism, and Internal Medicine with a preliminary diagnosis of Cushing’s syndrome. Computed tomography revealed a 27 mm left adrenal tumor, and she underwent laparoscopic adrenalectomy. She was admitted to hospital 6 months after this procedure, at which time she did not report any eating or mood disorder. This is a rare case report of a patient with anorexia nervosa in whom Cushing’s syndrome was subsequently diagnosed. Diagnostic difficulties were caused by the signs and symptoms presenting in the course of both disorders, ie, hypercortisolemia, osteoporosis, secondary amenorrhea, striae, hypokalemia, muscle weakness, and depression.Keywords: anorexia nervosa, Cushing’s syndrome, adrenalectomy, osteoporosis
format article
author Sawicka N
Gryczyńska M
Sowiński J
Tamborska-Zedlewska M
Ruchała M
author_facet Sawicka N
Gryczyńska M
Sowiński J
Tamborska-Zedlewska M
Ruchała M
author_sort Sawicka N
title Two diagnoses become one? Rare case report of anorexia nervosa and Cushing’s syndrome
title_short Two diagnoses become one? Rare case report of anorexia nervosa and Cushing’s syndrome
title_full Two diagnoses become one? Rare case report of anorexia nervosa and Cushing’s syndrome
title_fullStr Two diagnoses become one? Rare case report of anorexia nervosa and Cushing’s syndrome
title_full_unstemmed Two diagnoses become one? Rare case report of anorexia nervosa and Cushing’s syndrome
title_sort two diagnoses become one? rare case report of anorexia nervosa and cushing’s syndrome
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/ccdcd68402d64dbc9412752d475971bf
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