Fast and strong amplifiers of natural selection
Population structure can influence the probability of and time to fixation of new mutants. Here, Tkadlec et al. demonstrate mathematically that structures that increase fixation probability necessarily slow fixation, but also identify amplifying structures with minimal reductions in fixation time.
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Nature Portfolio
2021
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oai:doaj.org-article:ccdd4141d2804dc2a7b049dbf5a1f1762021-12-02T16:10:51ZFast and strong amplifiers of natural selection10.1038/s41467-021-24271-w2041-1723https://doaj.org/article/ccdd4141d2804dc2a7b049dbf5a1f1762021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24271-whttps://doaj.org/toc/2041-1723Population structure can influence the probability of and time to fixation of new mutants. Here, Tkadlec et al. demonstrate mathematically that structures that increase fixation probability necessarily slow fixation, but also identify amplifying structures with minimal reductions in fixation time.Josef TkadlecAndreas PavlogiannisKrishnendu ChatterjeeMartin A. NowakNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-6 (2021) |
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Science Q |
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Science Q Josef Tkadlec Andreas Pavlogiannis Krishnendu Chatterjee Martin A. Nowak Fast and strong amplifiers of natural selection |
description |
Population structure can influence the probability of and time to fixation of new mutants. Here, Tkadlec et al. demonstrate mathematically that structures that increase fixation probability necessarily slow fixation, but also identify amplifying structures with minimal reductions in fixation time. |
format |
article |
author |
Josef Tkadlec Andreas Pavlogiannis Krishnendu Chatterjee Martin A. Nowak |
author_facet |
Josef Tkadlec Andreas Pavlogiannis Krishnendu Chatterjee Martin A. Nowak |
author_sort |
Josef Tkadlec |
title |
Fast and strong amplifiers of natural selection |
title_short |
Fast and strong amplifiers of natural selection |
title_full |
Fast and strong amplifiers of natural selection |
title_fullStr |
Fast and strong amplifiers of natural selection |
title_full_unstemmed |
Fast and strong amplifiers of natural selection |
title_sort |
fast and strong amplifiers of natural selection |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/ccdd4141d2804dc2a7b049dbf5a1f176 |
work_keys_str_mv |
AT joseftkadlec fastandstrongamplifiersofnaturalselection AT andreaspavlogiannis fastandstrongamplifiersofnaturalselection AT krishnenduchatterjee fastandstrongamplifiersofnaturalselection AT martinanowak fastandstrongamplifiersofnaturalselection |
_version_ |
1718384438501441536 |