The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation

Abstract The COP9 signalosome (CSN) is an evolutionary conserved multiprotein complex that regulates many aspects of plant development by controlling the activity of CULLIN-RING E3 ubiquitin ligases (CRLs). CRLs ubiquitinate and target for proteasomal degradation a vast number of specific substrate...

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Autores principales:	Daniel Ioan Pacurar, Monica Lacramioara Pacurar, Abdellah Lakehal, Andrea Mariana Pacurar, Alok Ranjan, Catherine Bellini
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/cce8fe5fba7f4b538e3325f23f1ae57e
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spelling	oai:doaj.org-article:cce8fe5fba7f4b538e3325f23f1ae57e2021-12-02T12:31:50ZThe Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation10.1038/s41598-017-00744-12045-2322https://doaj.org/article/cce8fe5fba7f4b538e3325f23f1ae57e2017-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-00744-1https://doaj.org/toc/2045-2322Abstract The COP9 signalosome (CSN) is an evolutionary conserved multiprotein complex that regulates many aspects of plant development by controlling the activity of CULLIN-RING E3 ubiquitin ligases (CRLs). CRLs ubiquitinate and target for proteasomal degradation a vast number of specific substrate proteins involved in many developmental and physiological processes, including light and hormone signaling and cell division. As a consequence of CSN pleiotropic function, complete loss of CSN activity results in seedling lethality. Therefore, a detailed analysis of CSN physiological functions in adult Arabidopsis plants has been hampered by the early seedling lethality of csn null mutants. Here we report the identification and characterization of a viable allele of the Arabidopsis COP9 signalosome subunit 4 (CSN4). The allele, designated csn4-2035, suppresses the adventitious root (AR) phenotype of the Arabidopsis superroot2-1 mutant, potentially by altering its auxin signaling. Furthermore, we show that although the csn4-2035 mutation affects primary and lateral root (LR) formation in the 2035 suppressor mutant, CSN4 and other subunits of the COP9 complex seem to differentially control AR and LR development.Daniel Ioan PacurarMonica Lacramioara PacurarAbdellah LakehalAndrea Mariana PacurarAlok RanjanCatherine BelliniNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Daniel Ioan Pacurar Monica Lacramioara Pacurar Abdellah Lakehal Andrea Mariana Pacurar Alok Ranjan Catherine Bellini The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation
description	Abstract The COP9 signalosome (CSN) is an evolutionary conserved multiprotein complex that regulates many aspects of plant development by controlling the activity of CULLIN-RING E3 ubiquitin ligases (CRLs). CRLs ubiquitinate and target for proteasomal degradation a vast number of specific substrate proteins involved in many developmental and physiological processes, including light and hormone signaling and cell division. As a consequence of CSN pleiotropic function, complete loss of CSN activity results in seedling lethality. Therefore, a detailed analysis of CSN physiological functions in adult Arabidopsis plants has been hampered by the early seedling lethality of csn null mutants. Here we report the identification and characterization of a viable allele of the Arabidopsis COP9 signalosome subunit 4 (CSN4). The allele, designated csn4-2035, suppresses the adventitious root (AR) phenotype of the Arabidopsis superroot2-1 mutant, potentially by altering its auxin signaling. Furthermore, we show that although the csn4-2035 mutation affects primary and lateral root (LR) formation in the 2035 suppressor mutant, CSN4 and other subunits of the COP9 complex seem to differentially control AR and LR development.
format	article
author	Daniel Ioan Pacurar Monica Lacramioara Pacurar Abdellah Lakehal Andrea Mariana Pacurar Alok Ranjan Catherine Bellini
author_facet	Daniel Ioan Pacurar Monica Lacramioara Pacurar Abdellah Lakehal Andrea Mariana Pacurar Alok Ranjan Catherine Bellini
author_sort	Daniel Ioan Pacurar
title	The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation
title_short	The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation
title_full	The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation
title_fullStr	The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation
title_full_unstemmed	The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation
title_sort	arabidopsis cop9 signalosome subunit 4 (csn4) is involved in adventitious root formation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/cce8fe5fba7f4b538e3325f23f1ae57e
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The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation

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