Evolutionary instability of CUG-Leu in the genetic code of budding yeasts

The genetic code for amino acids is nearly universal, and among eukaryotic nuclear genomes the only known reassignments are of codon CUG in yeasts. Here, the authors identify a third independent CUG transition in budding yeasts that is still ongoing with alternative tRNAs present in the genome.

Guardado en:

Detalles Bibliográficos
Autores principales:	Tadeusz Krassowski, Aisling Y. Coughlan, Xing-Xing Shen, Xiaofan Zhou, Jacek Kominek, Dana A. Opulente, Robert Riley, Igor V. Grigoriev, Nikunj Maheshwari, Denis C. Shields, Cletus P. Kurtzman, Chris Todd Hittinger, Antonis Rokas, Kenneth H. Wolfe
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cced401e48ce421aa4209a2b5302837c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:cced401e48ce421aa4209a2b5302837c
record_format	dspace
spelling	oai:doaj.org-article:cced401e48ce421aa4209a2b5302837c2021-12-02T14:39:07ZEvolutionary instability of CUG-Leu in the genetic code of budding yeasts10.1038/s41467-018-04374-72041-1723https://doaj.org/article/cced401e48ce421aa4209a2b5302837c2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04374-7https://doaj.org/toc/2041-1723The genetic code for amino acids is nearly universal, and among eukaryotic nuclear genomes the only known reassignments are of codon CUG in yeasts. Here, the authors identify a third independent CUG transition in budding yeasts that is still ongoing with alternative tRNAs present in the genome.Tadeusz KrassowskiAisling Y. CoughlanXing-Xing ShenXiaofan ZhouJacek KominekDana A. OpulenteRobert RileyIgor V. GrigorievNikunj MaheshwariDenis C. ShieldsCletus P. KurtzmanChris Todd HittingerAntonis RokasKenneth H. WolfeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tadeusz Krassowski Aisling Y. Coughlan Xing-Xing Shen Xiaofan Zhou Jacek Kominek Dana A. Opulente Robert Riley Igor V. Grigoriev Nikunj Maheshwari Denis C. Shields Cletus P. Kurtzman Chris Todd Hittinger Antonis Rokas Kenneth H. Wolfe Evolutionary instability of CUG-Leu in the genetic code of budding yeasts
description	The genetic code for amino acids is nearly universal, and among eukaryotic nuclear genomes the only known reassignments are of codon CUG in yeasts. Here, the authors identify a third independent CUG transition in budding yeasts that is still ongoing with alternative tRNAs present in the genome.
format	article
author	Tadeusz Krassowski Aisling Y. Coughlan Xing-Xing Shen Xiaofan Zhou Jacek Kominek Dana A. Opulente Robert Riley Igor V. Grigoriev Nikunj Maheshwari Denis C. Shields Cletus P. Kurtzman Chris Todd Hittinger Antonis Rokas Kenneth H. Wolfe
author_facet	Tadeusz Krassowski Aisling Y. Coughlan Xing-Xing Shen Xiaofan Zhou Jacek Kominek Dana A. Opulente Robert Riley Igor V. Grigoriev Nikunj Maheshwari Denis C. Shields Cletus P. Kurtzman Chris Todd Hittinger Antonis Rokas Kenneth H. Wolfe
author_sort	Tadeusz Krassowski
title	Evolutionary instability of CUG-Leu in the genetic code of budding yeasts
title_short	Evolutionary instability of CUG-Leu in the genetic code of budding yeasts
title_full	Evolutionary instability of CUG-Leu in the genetic code of budding yeasts
title_fullStr	Evolutionary instability of CUG-Leu in the genetic code of budding yeasts
title_full_unstemmed	Evolutionary instability of CUG-Leu in the genetic code of budding yeasts
title_sort	evolutionary instability of cug-leu in the genetic code of budding yeasts
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/cced401e48ce421aa4209a2b5302837c
work_keys_str_mv	AT tadeuszkrassowski evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts AT aislingycoughlan evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts AT xingxingshen evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts AT xiaofanzhou evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts AT jacekkominek evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts AT danaaopulente evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts AT robertriley evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts AT igorvgrigoriev evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts AT nikunjmaheshwari evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts AT deniscshields evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts AT cletuspkurtzman evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts AT christoddhittinger evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts AT antonisrokas evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts AT kennethhwolfe evolutionaryinstabilityofcugleuinthegeneticcodeofbuddingyeasts
_version_	1718390738855657472

Evolutionary instability of CUG-Leu in the genetic code of budding yeasts

Ejemplares similares