Superactivation of AMPA receptors by auxiliary proteins

Transmembrane AMPA receptor regulatory proteins (TARPs) exert a number of effects on fast glutamatergic synaptic transmission. Here, the authors model the interactions of two such proteins, Stargazin and γ-8, and propose a simple kinetic mechanism by which TARPs modulate channel opening reaction.

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Detalles Bibliográficos
Autores principales:	Anna L. Carbone, Andrew J. R. Plested
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cced4a40fe934acba1c23a3b22a00e9b
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spelling	oai:doaj.org-article:cced4a40fe934acba1c23a3b22a00e9b2021-12-02T17:31:35ZSuperactivation of AMPA receptors by auxiliary proteins10.1038/ncomms101782041-1723https://doaj.org/article/cced4a40fe934acba1c23a3b22a00e9b2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10178https://doaj.org/toc/2041-1723Transmembrane AMPA receptor regulatory proteins (TARPs) exert a number of effects on fast glutamatergic synaptic transmission. Here, the authors model the interactions of two such proteins, Stargazin and γ-8, and propose a simple kinetic mechanism by which TARPs modulate channel opening reaction.Anna L. CarboneAndrew J. R. PlestedNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anna L. Carbone Andrew J. R. Plested Superactivation of AMPA receptors by auxiliary proteins
description	Transmembrane AMPA receptor regulatory proteins (TARPs) exert a number of effects on fast glutamatergic synaptic transmission. Here, the authors model the interactions of two such proteins, Stargazin and γ-8, and propose a simple kinetic mechanism by which TARPs modulate channel opening reaction.
format	article
author	Anna L. Carbone Andrew J. R. Plested
author_facet	Anna L. Carbone Andrew J. R. Plested
author_sort	Anna L. Carbone
title	Superactivation of AMPA receptors by auxiliary proteins
title_short	Superactivation of AMPA receptors by auxiliary proteins
title_full	Superactivation of AMPA receptors by auxiliary proteins
title_fullStr	Superactivation of AMPA receptors by auxiliary proteins
title_full_unstemmed	Superactivation of AMPA receptors by auxiliary proteins
title_sort	superactivation of ampa receptors by auxiliary proteins
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/cced4a40fe934acba1c23a3b22a00e9b
work_keys_str_mv	AT annalcarbone superactivationofampareceptorsbyauxiliaryproteins AT andrewjrplested superactivationofampareceptorsbyauxiliaryproteins
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Superactivation of AMPA receptors by auxiliary proteins

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