The transcriptional landscape of a rewritten bacterial genome reveals control elements and genome design principles

Rewriting genomes allows for complete annotation of gene regulatory elements. Here the authors compare endogenous and rewritten segments of a genome and find extensive transcriptional changes, based on which they formulate design principles that aid in the programming of biological systems.

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Autores principales: Mariëlle J. F. M. van Kooten, Clio A. Scheidegger, Matthias Christen, Beat Christen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ccf4854386d044bab964b2abe2e588e7
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