The transcriptional landscape of a rewritten bacterial genome reveals control elements and genome design principles
Rewriting genomes allows for complete annotation of gene regulatory elements. Here the authors compare endogenous and rewritten segments of a genome and find extensive transcriptional changes, based on which they formulate design principles that aid in the programming of biological systems.
Guardado en:
Autores principales: | Mariëlle J. F. M. van Kooten, Clio A. Scheidegger, Matthias Christen, Beat Christen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/ccf4854386d044bab964b2abe2e588e7 |
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