Long-term body mass trajectories and hypertension by sex among Chinese adults: a 24-year open cohort study

Abstract Evidence was limited on trajectory of body mass index (BMI) through adulthood and its association with hypertension. We aimed to evaluate their association by sex in large-scale study. Data were obtained from the China Health and Nutrition Survey (CHNS) from 1991 to 2015. Latent class traje...

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Autores principales: Ruru Liu, Baibing Mi, Yaling Zhao, Shaonong Dang, Hong Yan
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ccfa7033c70e4ab3b1ef74f32f1c24f2
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spelling oai:doaj.org-article:ccfa7033c70e4ab3b1ef74f32f1c24f22021-12-02T17:45:03ZLong-term body mass trajectories and hypertension by sex among Chinese adults: a 24-year open cohort study10.1038/s41598-021-92319-42045-2322https://doaj.org/article/ccfa7033c70e4ab3b1ef74f32f1c24f22021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-92319-4https://doaj.org/toc/2045-2322Abstract Evidence was limited on trajectory of body mass index (BMI) through adulthood and its association with hypertension. We aimed to evaluate their association by sex in large-scale study. Data were obtained from the China Health and Nutrition Survey (CHNS) from 1991 to 2015. Latent class trajectory analysis (LCTA) was used to capture BMI change trajectories. Hazard risks (HRs) were estimated from Cox proportion hazard regression. Among 14,262 participants (mean age, 38.8; 47.8% men), 5138 hypertension occurred (2687 men and 2451 women) occurred during a mean follow-up 9.6 years. Four body mass trajectory groups were identified as BMI loss, stable, moderate and substantial gain. Appropriately half of participants (48.0%) followed 1 of the 2 BMI gain trajectories, where BMI increased at least 3 kg/m2 overtime. Compared with participants with stable BMI, those gaining BMI substantially had higher risk of hypertension by 65% (HR 1.65, 95% CI 1.45–1.86) in male and 83% (HR 1.83, 95% CI 1.58–2.12) in female. The HRs in BMI loss patterns were 0.74 (0.62–0.89) in men and 0.87 (0.75–1.00) in women. Our findings imply that majority of Chinese adults transited up to a higher BMI level during follow-up. Avoiding excessive weight gain and maintaining stable weight might be important for hypertension prevention.Ruru LiuBaibing MiYaling ZhaoShaonong DangHong YanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Ruru Liu
Baibing Mi
Yaling Zhao
Shaonong Dang
Hong Yan
Long-term body mass trajectories and hypertension by sex among Chinese adults: a 24-year open cohort study
description Abstract Evidence was limited on trajectory of body mass index (BMI) through adulthood and its association with hypertension. We aimed to evaluate their association by sex in large-scale study. Data were obtained from the China Health and Nutrition Survey (CHNS) from 1991 to 2015. Latent class trajectory analysis (LCTA) was used to capture BMI change trajectories. Hazard risks (HRs) were estimated from Cox proportion hazard regression. Among 14,262 participants (mean age, 38.8; 47.8% men), 5138 hypertension occurred (2687 men and 2451 women) occurred during a mean follow-up 9.6 years. Four body mass trajectory groups were identified as BMI loss, stable, moderate and substantial gain. Appropriately half of participants (48.0%) followed 1 of the 2 BMI gain trajectories, where BMI increased at least 3 kg/m2 overtime. Compared with participants with stable BMI, those gaining BMI substantially had higher risk of hypertension by 65% (HR 1.65, 95% CI 1.45–1.86) in male and 83% (HR 1.83, 95% CI 1.58–2.12) in female. The HRs in BMI loss patterns were 0.74 (0.62–0.89) in men and 0.87 (0.75–1.00) in women. Our findings imply that majority of Chinese adults transited up to a higher BMI level during follow-up. Avoiding excessive weight gain and maintaining stable weight might be important for hypertension prevention.
format article
author Ruru Liu
Baibing Mi
Yaling Zhao
Shaonong Dang
Hong Yan
author_facet Ruru Liu
Baibing Mi
Yaling Zhao
Shaonong Dang
Hong Yan
author_sort Ruru Liu
title Long-term body mass trajectories and hypertension by sex among Chinese adults: a 24-year open cohort study
title_short Long-term body mass trajectories and hypertension by sex among Chinese adults: a 24-year open cohort study
title_full Long-term body mass trajectories and hypertension by sex among Chinese adults: a 24-year open cohort study
title_fullStr Long-term body mass trajectories and hypertension by sex among Chinese adults: a 24-year open cohort study
title_full_unstemmed Long-term body mass trajectories and hypertension by sex among Chinese adults: a 24-year open cohort study
title_sort long-term body mass trajectories and hypertension by sex among chinese adults: a 24-year open cohort study
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/ccfa7033c70e4ab3b1ef74f32f1c24f2
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