Multi-Omic Analyses Provide Links between Low-Dose Antibiotic Treatment and Induction of Secondary Metabolism in <named-content content-type="genus-species">Burkholderia thailandensis</named-content>

Multi-Omic Analyses Provide Links between Low-Dose Antibiotic Treatment and Induction of Secondary Metabolism in <named-content content-type="genus-species">Burkholderia thailandensis</named-content>

ABSTRACT Low doses of antibiotics can trigger secondary metabolite biosynthesis in bacteria, but the underlying mechanisms are generally unknown. We sought to better understand this phenomenon by studying how the antibiotic trimethoprim activates the synthesis of the virulence factor malleilactone i...

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Autores principales: Anran Li, Dainan Mao, Aya Yoshimura, Paul C. Rosen, W. Lance Martin, Étienne Gallant, Martin Wühr, Mohammad R. Seyedsayamdost
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
antibiotics
biosynthesis
natural products
secondary metabolism
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/ccfb72223b13473a8b3d92fb7f6da58d
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