Use of Intraoperative Frozen Section in the Surgical Management of Patients with Nonmelanoma Skin Cancer

Background. Intraoperative frozen section (IFS) is often utilised in the surgical treatment of nonmelanocytic skin cancer (NMSC) in sensitive facial regions when Mohs micrographic surgery (MMS) is not available. Objective. To compare the outcome of NMSC patients with excision performed with and with...

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Autores principales:	LiAnn Loh, Priya Tiwari, Jingtzer Lee, O-Wern Low, Vigneswaran Nallathamby, Hanjing Lee, Jane Lim, Thiam Chye Lim, Yan Lin Yap
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/ccfc9197350d4164bd7a55dd36b56f22
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spelling	oai:doaj.org-article:ccfc9197350d4164bd7a55dd36b56f222021-11-15T01:19:38ZUse of Intraoperative Frozen Section in the Surgical Management of Patients with Nonmelanoma Skin Cancer2090-291310.1155/2021/4944570https://doaj.org/article/ccfc9197350d4164bd7a55dd36b56f222021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/4944570https://doaj.org/toc/2090-2913Background. Intraoperative frozen section (IFS) is often utilised in the surgical treatment of nonmelanocytic skin cancer (NMSC) in sensitive facial regions when Mohs micrographic surgery (MMS) is not available. Objective. To compare the outcome of NMSC patients with excision performed with and without IFS. Materials and Methods. A retrospective, single-centre study was performed on all patients who had undergone resection of NMSC with and without IFS control at the National University Hospital (NUH) from 2010 to 2015. Results. 116 patients were recruited, of which 86 had IFS and 30 did not. The complete excision rate of patients with IFS was higher at 87.2% (p=0.0194), need for secondary operation was lower at 1.2% (p=0.005), and need for postsurgery radiotherapy or chemotherapy was lower at 1.2% (p=0.001). The average duration of surgery in patients who underwent IFS was 95.4 minutes compared to 70.1 minutes in cases which did not undergo IFS. Conclusion. Our study showed an increased complete excision rate and reduced need for secondary surgeries and adjuvant therapy in patients with IFS. However, a longer operative duration was required. Use of IFS may be useful in patients with NMSC lesions in sensitive regions requiring complex reconstruction after tumour excision.LiAnn LohPriya TiwariJingtzer LeeO-Wern LowVigneswaran NallathambyHanjing LeeJane LimThiam Chye LimYan Lin YapHindawi LimitedarticleNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENJournal of Skin Cancer, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 LiAnn Loh Priya Tiwari Jingtzer Lee O-Wern Low Vigneswaran Nallathamby Hanjing Lee Jane Lim Thiam Chye Lim Yan Lin Yap Use of Intraoperative Frozen Section in the Surgical Management of Patients with Nonmelanoma Skin Cancer
description	Background. Intraoperative frozen section (IFS) is often utilised in the surgical treatment of nonmelanocytic skin cancer (NMSC) in sensitive facial regions when Mohs micrographic surgery (MMS) is not available. Objective. To compare the outcome of NMSC patients with excision performed with and without IFS. Materials and Methods. A retrospective, single-centre study was performed on all patients who had undergone resection of NMSC with and without IFS control at the National University Hospital (NUH) from 2010 to 2015. Results. 116 patients were recruited, of which 86 had IFS and 30 did not. The complete excision rate of patients with IFS was higher at 87.2% (p=0.0194), need for secondary operation was lower at 1.2% (p=0.005), and need for postsurgery radiotherapy or chemotherapy was lower at 1.2% (p=0.001). The average duration of surgery in patients who underwent IFS was 95.4 minutes compared to 70.1 minutes in cases which did not undergo IFS. Conclusion. Our study showed an increased complete excision rate and reduced need for secondary surgeries and adjuvant therapy in patients with IFS. However, a longer operative duration was required. Use of IFS may be useful in patients with NMSC lesions in sensitive regions requiring complex reconstruction after tumour excision.
format	article
author	LiAnn Loh Priya Tiwari Jingtzer Lee O-Wern Low Vigneswaran Nallathamby Hanjing Lee Jane Lim Thiam Chye Lim Yan Lin Yap
author_facet	LiAnn Loh Priya Tiwari Jingtzer Lee O-Wern Low Vigneswaran Nallathamby Hanjing Lee Jane Lim Thiam Chye Lim Yan Lin Yap
author_sort	LiAnn Loh
title	Use of Intraoperative Frozen Section in the Surgical Management of Patients with Nonmelanoma Skin Cancer
title_short	Use of Intraoperative Frozen Section in the Surgical Management of Patients with Nonmelanoma Skin Cancer
title_full	Use of Intraoperative Frozen Section in the Surgical Management of Patients with Nonmelanoma Skin Cancer
title_fullStr	Use of Intraoperative Frozen Section in the Surgical Management of Patients with Nonmelanoma Skin Cancer
title_full_unstemmed	Use of Intraoperative Frozen Section in the Surgical Management of Patients with Nonmelanoma Skin Cancer
title_sort	use of intraoperative frozen section in the surgical management of patients with nonmelanoma skin cancer
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/ccfc9197350d4164bd7a55dd36b56f22
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Use of Intraoperative Frozen Section in the Surgical Management of Patients with Nonmelanoma Skin Cancer

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