MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording
Fiber optic implantation in deep areas of the rodent’s brain for MRI combined with optogenetics is challenging. Here the authors use an MRI-guided robotic arm as the navigation method for accurate fiber optic placement and precise microinjection during multi-modal fMRI, optogenetics and calcium reco...
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Nature Portfolio
2019
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oai:doaj.org-article:ccfe8e12e17e45b59013aa354bf7d3632021-12-02T14:39:41ZMRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording10.1038/s41467-019-10450-32041-1723https://doaj.org/article/ccfe8e12e17e45b59013aa354bf7d3632019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10450-3https://doaj.org/toc/2041-1723Fiber optic implantation in deep areas of the rodent’s brain for MRI combined with optogenetics is challenging. Here the authors use an MRI-guided robotic arm as the navigation method for accurate fiber optic placement and precise microinjection during multi-modal fMRI, optogenetics and calcium recordings.Yi ChenPatricia Pais-RoldanXuming ChenMichael H. FroszXin YuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019) |
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Science Q Yi Chen Patricia Pais-Roldan Xuming Chen Michael H. Frosz Xin Yu MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording |
description |
Fiber optic implantation in deep areas of the rodent’s brain for MRI combined with optogenetics is challenging. Here the authors use an MRI-guided robotic arm as the navigation method for accurate fiber optic placement and precise microinjection during multi-modal fMRI, optogenetics and calcium recordings. |
format |
article |
author |
Yi Chen Patricia Pais-Roldan Xuming Chen Michael H. Frosz Xin Yu |
author_facet |
Yi Chen Patricia Pais-Roldan Xuming Chen Michael H. Frosz Xin Yu |
author_sort |
Yi Chen |
title |
MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording |
title_short |
MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording |
title_full |
MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording |
title_fullStr |
MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording |
title_full_unstemmed |
MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording |
title_sort |
mri-guided robotic arm drives optogenetic fmri with concurrent ca2+ recording |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/ccfe8e12e17e45b59013aa354bf7d363 |
work_keys_str_mv |
AT yichen mriguidedroboticarmdrivesoptogeneticfmriwithconcurrentca2recording AT patriciapaisroldan mriguidedroboticarmdrivesoptogeneticfmriwithconcurrentca2recording AT xumingchen mriguidedroboticarmdrivesoptogeneticfmriwithconcurrentca2recording AT michaelhfrosz mriguidedroboticarmdrivesoptogeneticfmriwithconcurrentca2recording AT xinyu mriguidedroboticarmdrivesoptogeneticfmriwithconcurrentca2recording |
_version_ |
1718390559141265408 |