MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording

Fiber optic implantation in deep areas of the rodent’s brain for MRI combined with optogenetics is challenging. Here the authors use an MRI-guided robotic arm as the navigation method for accurate fiber optic placement and precise microinjection during multi-modal fMRI, optogenetics and calcium reco...

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Autores principales: Yi Chen, Patricia Pais-Roldan, Xuming Chen, Michael H. Frosz, Xin Yu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/ccfe8e12e17e45b59013aa354bf7d363
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spelling oai:doaj.org-article:ccfe8e12e17e45b59013aa354bf7d3632021-12-02T14:39:41ZMRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording10.1038/s41467-019-10450-32041-1723https://doaj.org/article/ccfe8e12e17e45b59013aa354bf7d3632019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10450-3https://doaj.org/toc/2041-1723Fiber optic implantation in deep areas of the rodent’s brain for MRI combined with optogenetics is challenging. Here the authors use an MRI-guided robotic arm as the navigation method for accurate fiber optic placement and precise microinjection during multi-modal fMRI, optogenetics and calcium recordings.Yi ChenPatricia Pais-RoldanXuming ChenMichael H. FroszXin YuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yi Chen
Patricia Pais-Roldan
Xuming Chen
Michael H. Frosz
Xin Yu
MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording
description Fiber optic implantation in deep areas of the rodent’s brain for MRI combined with optogenetics is challenging. Here the authors use an MRI-guided robotic arm as the navigation method for accurate fiber optic placement and precise microinjection during multi-modal fMRI, optogenetics and calcium recordings.
format article
author Yi Chen
Patricia Pais-Roldan
Xuming Chen
Michael H. Frosz
Xin Yu
author_facet Yi Chen
Patricia Pais-Roldan
Xuming Chen
Michael H. Frosz
Xin Yu
author_sort Yi Chen
title MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording
title_short MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording
title_full MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording
title_fullStr MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording
title_full_unstemmed MRI-guided robotic arm drives optogenetic fMRI with concurrent Ca2+ recording
title_sort mri-guided robotic arm drives optogenetic fmri with concurrent ca2+ recording
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/ccfe8e12e17e45b59013aa354bf7d363
work_keys_str_mv AT yichen mriguidedroboticarmdrivesoptogeneticfmriwithconcurrentca2recording
AT patriciapaisroldan mriguidedroboticarmdrivesoptogeneticfmriwithconcurrentca2recording
AT xumingchen mriguidedroboticarmdrivesoptogeneticfmriwithconcurrentca2recording
AT michaelhfrosz mriguidedroboticarmdrivesoptogeneticfmriwithconcurrentca2recording
AT xinyu mriguidedroboticarmdrivesoptogeneticfmriwithconcurrentca2recording
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