Involvement of dynamin-related protein 1 in free fatty acid-induced INS-1-derived cell apoptosis.

Involvement of dynamin-related protein 1 in free fatty acid-induced INS-1-derived cell apoptosis.

Elevated extracellular free fatty acids (FFAs) can induce pancreatic beta cell apoptosis, thereby contributing to the pathogenesis of type 2 diabetes mellitus (T2D). Mitochondrial dysfunction has been implicated in FFA-induced beta cell apoptosis. However, molecular mechanisms linking mitochondrial...

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Autores principales: Liang Peng, Xiuli Men, Wenjian Zhang, Haiyan Wang, Shiqing Xu, Qing Fang, Honglin Liu, Wenying Yang, Jinning Lou
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/cd19bf199059401fa2d602abc0109dc0
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