C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKCα complex and cerebellar plasticity.

C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKCα complex and cerebellar plasticity.

<h4>Background</h4>PICK1 (protein interacting with C-kinase 1) is a PKC (protein kinase C)-binding protein, which is essential for synaptic plasticity. The trafficking of PKCα-PICK1 complex to plasma membrane is critical for the internalization of GluR2 and induction of long-term depress...

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Main Authors: Zhen Wang, Ya-Nan Wang, Cheng-Long Sun, Dong Yang, Li-Da Su, Ya-Jun Xie, Lin Zhou, Yin Wang, Ying Shen
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
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Science
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Online Access:https://doaj.org/article/cd1fc9e18d3d4622bcedaae47a1d95ff
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