Lower conjunctival fornix packing for mydriasis in premature infants: a randomized trial

Onsiri Thanathanee1, Tanapat Ratanapakorn1, Michael G Morley2, Yosanan Yospaiboon11Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 2Harvard Medical School, Boston, MA, USAObjective: To compare the mydriatic effect of lower conjunctival fornix packing to c...

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Autores principales: Morley MG, Ratanapakorn T, Thanathanee O, Yospaiboon Y
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Publicado: Dove Medical Press 2012
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spelling oai:doaj.org-article:cd24b256c43d4b268927d7cefdf912de2021-12-02T08:10:34ZLower conjunctival fornix packing for mydriasis in premature infants: a randomized trial1177-54671177-5483https://doaj.org/article/cd24b256c43d4b268927d7cefdf912de2012-02-01T00:00:00Zhttp://www.dovepress.com/lower-conjunctival-fornix-packing-for-mydriasis-in-premature-infants-a-a9267https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Onsiri Thanathanee1, Tanapat Ratanapakorn1, Michael G Morley2, Yosanan Yospaiboon11Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 2Harvard Medical School, Boston, MA, USAObjective: To compare the mydriatic effect of lower conjunctival fornix packing to conventional instillation of eyedrops containing 2.5% phenylephrine and 1% tropicamide in premature infants undergoing examination for retinopathy of prematurity.Methods: The patients were randomized to receive either conventional instillation of mydriatic drops or lower conjunctival fornix packing in one eye and the alternate method in the fellow eye. For the eyes receiving lower conjunctival fornix packing (study group), one small piece of the cotton wool soaked with one drop of 2.5% phenylephrine and one drop of 1% tropicamide was packed in the lower conjunctival fornix for 15 minutes. For the eyes receiving the conventional instillation (control group), 2.5% phenylephrine and 1% tropicamide were alternately instilled every 5 minutes for two doses each. Horizontal pupil diameter was measured with a ruler in millimeters 40 minutes later.Results: The mean dilated pupil diameter in study group and control group were 5.76 ± 1.01 mm and 4.50 ± 1.08 mm, respectively. This difference was statistically significant (P < 0.05).Conclusion: The dilated pupil diameter after receiving the lower conjunctival fornix packing was larger than conventional instillation with a statistically significant difference. We recommended the packing method to dilate the preterm infant pupil, especially if the pupil is difficult to dilate.Keywords: conjunctival fornix packing, phenylephrine, mydriasis, premature infantsMorley MGRatanapakorn TThanathanee OYospaiboon YDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 253-256 (2012)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Morley MG
Ratanapakorn T
Thanathanee O
Yospaiboon Y
Lower conjunctival fornix packing for mydriasis in premature infants: a randomized trial
description Onsiri Thanathanee1, Tanapat Ratanapakorn1, Michael G Morley2, Yosanan Yospaiboon11Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 2Harvard Medical School, Boston, MA, USAObjective: To compare the mydriatic effect of lower conjunctival fornix packing to conventional instillation of eyedrops containing 2.5% phenylephrine and 1% tropicamide in premature infants undergoing examination for retinopathy of prematurity.Methods: The patients were randomized to receive either conventional instillation of mydriatic drops or lower conjunctival fornix packing in one eye and the alternate method in the fellow eye. For the eyes receiving lower conjunctival fornix packing (study group), one small piece of the cotton wool soaked with one drop of 2.5% phenylephrine and one drop of 1% tropicamide was packed in the lower conjunctival fornix for 15 minutes. For the eyes receiving the conventional instillation (control group), 2.5% phenylephrine and 1% tropicamide were alternately instilled every 5 minutes for two doses each. Horizontal pupil diameter was measured with a ruler in millimeters 40 minutes later.Results: The mean dilated pupil diameter in study group and control group were 5.76 ± 1.01 mm and 4.50 ± 1.08 mm, respectively. This difference was statistically significant (P < 0.05).Conclusion: The dilated pupil diameter after receiving the lower conjunctival fornix packing was larger than conventional instillation with a statistically significant difference. We recommended the packing method to dilate the preterm infant pupil, especially if the pupil is difficult to dilate.Keywords: conjunctival fornix packing, phenylephrine, mydriasis, premature infants
format article
author Morley MG
Ratanapakorn T
Thanathanee O
Yospaiboon Y
author_facet Morley MG
Ratanapakorn T
Thanathanee O
Yospaiboon Y
author_sort Morley MG
title Lower conjunctival fornix packing for mydriasis in premature infants: a randomized trial
title_short Lower conjunctival fornix packing for mydriasis in premature infants: a randomized trial
title_full Lower conjunctival fornix packing for mydriasis in premature infants: a randomized trial
title_fullStr Lower conjunctival fornix packing for mydriasis in premature infants: a randomized trial
title_full_unstemmed Lower conjunctival fornix packing for mydriasis in premature infants: a randomized trial
title_sort lower conjunctival fornix packing for mydriasis in premature infants: a randomized trial
publisher Dove Medical Press
publishDate 2012
url https://doaj.org/article/cd24b256c43d4b268927d7cefdf912de
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