Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells

Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells

Summary: Myeloid suppressor cells promote tumor growth by a variety of mechanisms which are not fully characterized. We identified myeloid cells (MCs) expressing the latency-associated peptide (LAP) of TGF-β on their surface and LAPHi MCs that stimulate Foxp3+ Tregs while inhibiting effector T cell...

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Bibliographic Details
Main Authors: Galina Gabriely, Duanduan Ma, Shafiuddin Siddiqui, Linqing Sun, Nathaniel P. Skillin, Hadi Abou-El-Hassan, Thais G. Moreira, Dustin Donnelly, Andre P. da Cunha, Mai Fujiwara, Lena R. Walton, Amee Patel, Rajesh Krishnan, Stuart S. Levine, Brian C. Healy, Rafael M. Rezende, Gopal Murugaiyan, Howard L. Weiner
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Immunology
Cancer
Science
Q
Online Access:https://doaj.org/article/cd2b4250e05d4e979dda9bd8430b32ec
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