Predictors of quality of life among individuals with schizophrenia

Sirijit Suttajit, Sutrak Pilakanta Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Purpose: The study reported here aimed to evaluate both biological and psychosocial factors as predictors for quality of life as well as to examine the associations between...

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Autores principales:	Suttajit S, Pilakanta S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/cd2ccfb02ad7436eaf0d76c66834f305
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spelling	oai:doaj.org-article:cd2ccfb02ad7436eaf0d76c66834f3052021-12-02T05:28:21ZPredictors of quality of life among individuals with schizophrenia1178-2021https://doaj.org/article/cd2ccfb02ad7436eaf0d76c66834f3052015-05-01T00:00:00Zhttp://www.dovepress.com/predictors-of-quality-of-life-among-individuals-with-schizophrenia-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Sirijit Suttajit, Sutrak Pilakanta Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Purpose: The study reported here aimed to evaluate both biological and psychosocial factors as predictors for quality of life as well as to examine the associations between the factors and quality of life in individuals with schizophrenia. Methods: Eighty individuals with schizophrenia were recruited to the study. The Thai version of the World Health Organization Quality of Life-BREF was utilized to measure the quality of life. The five Marder subscales of the Positive and Negative Syndrome Scale were applied. Other tools for measurement included the Calgary Depression Scale for Schizophrenia and six social support deficits (SSDs). Pearson/Spearman correlation coefficients and the independent t-test were used for the statistical analysis to determine the associations of variables and the overall quality of life and the four domain scores. A multiple linear regression analysis of the overall quality of life and four domain scores was applied to determine their predictors. Results: The Positive and Negative Syndrome Scale total score, positive symptoms, negative symptoms, disorganized thought, and anxiety/depression showed a significant correlation with the overall quality of life and most of the four domain scores. Depression, SSDs, and adverse drug events showed a significant correlation with a poorer overall quality of life. The multiple linear regression model revealed that negative symptoms, depression, and seeing a relative less often than once per week were predictors for the overall quality of life (adjusted R2=0.472). Negative symptoms were also found to be the main factors predicting a decrease in the four domains of quality of life – physical health, psychological, social relationships, and environment. Conclusion: Negative symptoms, depression, and poor contact with relatives were the foremost predictors of poor quality of life in individuals with schizophrenia. Positive symptoms, negative symptoms, disorganized thought, anxiety/depression, SSDs, and adverse events were also found to be correlated with quality of life. Keywords: adverse events, depression, negative symptoms, positive symptoms, social supportSuttajit SPilakanta SDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2015, Iss default, Pp 1371-1379 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Suttajit S Pilakanta S Predictors of quality of life among individuals with schizophrenia
description	Sirijit Suttajit, Sutrak Pilakanta Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Purpose: The study reported here aimed to evaluate both biological and psychosocial factors as predictors for quality of life as well as to examine the associations between the factors and quality of life in individuals with schizophrenia. Methods: Eighty individuals with schizophrenia were recruited to the study. The Thai version of the World Health Organization Quality of Life-BREF was utilized to measure the quality of life. The five Marder subscales of the Positive and Negative Syndrome Scale were applied. Other tools for measurement included the Calgary Depression Scale for Schizophrenia and six social support deficits (SSDs). Pearson/Spearman correlation coefficients and the independent t-test were used for the statistical analysis to determine the associations of variables and the overall quality of life and the four domain scores. A multiple linear regression analysis of the overall quality of life and four domain scores was applied to determine their predictors. Results: The Positive and Negative Syndrome Scale total score, positive symptoms, negative symptoms, disorganized thought, and anxiety/depression showed a significant correlation with the overall quality of life and most of the four domain scores. Depression, SSDs, and adverse drug events showed a significant correlation with a poorer overall quality of life. The multiple linear regression model revealed that negative symptoms, depression, and seeing a relative less often than once per week were predictors for the overall quality of life (adjusted R2=0.472). Negative symptoms were also found to be the main factors predicting a decrease in the four domains of quality of life – physical health, psychological, social relationships, and environment. Conclusion: Negative symptoms, depression, and poor contact with relatives were the foremost predictors of poor quality of life in individuals with schizophrenia. Positive symptoms, negative symptoms, disorganized thought, anxiety/depression, SSDs, and adverse events were also found to be correlated with quality of life. Keywords: adverse events, depression, negative symptoms, positive symptoms, social support
format	article
author	Suttajit S Pilakanta S
author_facet	Suttajit S Pilakanta S
author_sort	Suttajit S
title	Predictors of quality of life among individuals with schizophrenia
title_short	Predictors of quality of life among individuals with schizophrenia
title_full	Predictors of quality of life among individuals with schizophrenia
title_fullStr	Predictors of quality of life among individuals with schizophrenia
title_full_unstemmed	Predictors of quality of life among individuals with schizophrenia
title_sort	predictors of quality of life among individuals with schizophrenia
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/cd2ccfb02ad7436eaf0d76c66834f305
work_keys_str_mv	AT suttajits predictorsofqualityoflifeamongindividualswithschizophrenia AT pilakantas predictorsofqualityoflifeamongindividualswithschizophrenia
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Predictors of quality of life among individuals with schizophrenia

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