Thiol/redox metabolomic profiling implicates GSH dysregulation in early experimental graft versus host disease (GVHD).
Graft-versus-host disease (GVHD) is a common complication of allogeneic bone marrow transplantation (BMT). Upregulation of inflammatory cytokines precedes the clinical presentation of GVHD and predicts its severity. In this report, thiol/redox metabolomics was used to identify metabolic perturbation...
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Auteurs principaux: | Jung H Suh, Bindu Kanathezhath, Swapna Shenvi, Hua Guo, Alicia Zhou, Anureet Tiwana, Frans Kuypers, Bruce N Ames, Mark C Walters |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2014
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Sujets: | |
Accès en ligne: | https://doaj.org/article/cd30e02e0ee641df88cfec7f2bde2f2d |
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