FABP4 as a key determinant of metastatic potential of ovarian cancer

In ovarian cancer, metastatic phenotype may impact surgical outcomes. Here, the authors show miR-409-3p regulates FABP4 which can increase metastatic potential of ovarian cancer, and treatment with DOPC nanoliposomes containing either miR-409--3p mimic or FABP4 siRNA inhibits tumor progression in mi...

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Autores principales:	Kshipra M. Gharpure, Sunila Pradeep, Marta Sans, Rajesha Rupaimoole, Cristina Ivan, Sherry Y. Wu, Emine Bayraktar, Archana S. Nagaraja, Lingegowda S. Mangala, Xinna Zhang, Monika Haemmerle, Wei Hu, Cristian Rodriguez-Aguayo, Michael McGuire, Celia Sze Ling Mak, Xiuhui Chen, Michelle A. Tran, Alejandro Villar-Prados, Guillermo Armaiz Pena, Ragini Kondetimmanahalli, Ryan Nini, Pranavi Koppula, Prahlad Ram, Jinsong Liu, Gabriel Lopez-Berestein, Keith Baggerly, Livia S. Eberlin, Anil K. Sood
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cd4daa013b304a3bac89c32615717550
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spelling	oai:doaj.org-article:cd4daa013b304a3bac89c326157175502021-12-02T15:34:39ZFABP4 as a key determinant of metastatic potential of ovarian cancer10.1038/s41467-018-04987-y2041-1723https://doaj.org/article/cd4daa013b304a3bac89c326157175502018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04987-yhttps://doaj.org/toc/2041-1723In ovarian cancer, metastatic phenotype may impact surgical outcomes. Here, the authors show miR-409-3p regulates FABP4 which can increase metastatic potential of ovarian cancer, and treatment with DOPC nanoliposomes containing either miR-409--3p mimic or FABP4 siRNA inhibits tumor progression in mice.Kshipra M. GharpureSunila PradeepMarta SansRajesha RupaimooleCristina IvanSherry Y. WuEmine BayraktarArchana S. NagarajaLingegowda S. MangalaXinna ZhangMonika HaemmerleWei HuCristian Rodriguez-AguayoMichael McGuireCelia Sze Ling MakXiuhui ChenMichelle A. TranAlejandro Villar-PradosGuillermo Armaiz PenaRagini KondetimmanahalliRyan NiniPranavi KoppulaPrahlad RamJinsong LiuGabriel Lopez-BeresteinKeith BaggerlyLivia S. EberlinAnil K. SoodNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kshipra M. Gharpure Sunila Pradeep Marta Sans Rajesha Rupaimoole Cristina Ivan Sherry Y. Wu Emine Bayraktar Archana S. Nagaraja Lingegowda S. Mangala Xinna Zhang Monika Haemmerle Wei Hu Cristian Rodriguez-Aguayo Michael McGuire Celia Sze Ling Mak Xiuhui Chen Michelle A. Tran Alejandro Villar-Prados Guillermo Armaiz Pena Ragini Kondetimmanahalli Ryan Nini Pranavi Koppula Prahlad Ram Jinsong Liu Gabriel Lopez-Berestein Keith Baggerly Livia S. Eberlin Anil K. Sood FABP4 as a key determinant of metastatic potential of ovarian cancer
description	In ovarian cancer, metastatic phenotype may impact surgical outcomes. Here, the authors show miR-409-3p regulates FABP4 which can increase metastatic potential of ovarian cancer, and treatment with DOPC nanoliposomes containing either miR-409--3p mimic or FABP4 siRNA inhibits tumor progression in mice.
format	article
author	Kshipra M. Gharpure Sunila Pradeep Marta Sans Rajesha Rupaimoole Cristina Ivan Sherry Y. Wu Emine Bayraktar Archana S. Nagaraja Lingegowda S. Mangala Xinna Zhang Monika Haemmerle Wei Hu Cristian Rodriguez-Aguayo Michael McGuire Celia Sze Ling Mak Xiuhui Chen Michelle A. Tran Alejandro Villar-Prados Guillermo Armaiz Pena Ragini Kondetimmanahalli Ryan Nini Pranavi Koppula Prahlad Ram Jinsong Liu Gabriel Lopez-Berestein Keith Baggerly Livia S. Eberlin Anil K. Sood
author_facet	Kshipra M. Gharpure Sunila Pradeep Marta Sans Rajesha Rupaimoole Cristina Ivan Sherry Y. Wu Emine Bayraktar Archana S. Nagaraja Lingegowda S. Mangala Xinna Zhang Monika Haemmerle Wei Hu Cristian Rodriguez-Aguayo Michael McGuire Celia Sze Ling Mak Xiuhui Chen Michelle A. Tran Alejandro Villar-Prados Guillermo Armaiz Pena Ragini Kondetimmanahalli Ryan Nini Pranavi Koppula Prahlad Ram Jinsong Liu Gabriel Lopez-Berestein Keith Baggerly Livia S. Eberlin Anil K. Sood
author_sort	Kshipra M. Gharpure
title	FABP4 as a key determinant of metastatic potential of ovarian cancer
title_short	FABP4 as a key determinant of metastatic potential of ovarian cancer
title_full	FABP4 as a key determinant of metastatic potential of ovarian cancer
title_fullStr	FABP4 as a key determinant of metastatic potential of ovarian cancer
title_full_unstemmed	FABP4 as a key determinant of metastatic potential of ovarian cancer
title_sort	fabp4 as a key determinant of metastatic potential of ovarian cancer
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/cd4daa013b304a3bac89c32615717550
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FABP4 as a key determinant of metastatic potential of ovarian cancer

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