Identifying occult bladder outlet obstruction in women with detrusor-underactivity-like urodynamic profiles

Abstract Voiding dysfunction can result from detrusor underactivity (DU), bladder outlet obstruction (BOO), or both. Conceptually, women with high-pressure low-flow urodynamic profiles are diagnosed with BOO without DU. However, the possibility of BOO is often neglected in women with DU-like (low-pr...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Po-Ming Chow, Sheng-Mou Hsiao, Hann-Chorng Kuo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/cd57e7ad04344a78868d555d68941a70
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:cd57e7ad04344a78868d555d68941a70
record_format	dspace
spelling	oai:doaj.org-article:cd57e7ad04344a78868d555d68941a702021-12-05T12:12:09ZIdentifying occult bladder outlet obstruction in women with detrusor-underactivity-like urodynamic profiles10.1038/s41598-021-02617-02045-2322https://doaj.org/article/cd57e7ad04344a78868d555d68941a702021-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02617-0https://doaj.org/toc/2045-2322Abstract Voiding dysfunction can result from detrusor underactivity (DU), bladder outlet obstruction (BOO), or both. Conceptually, women with high-pressure low-flow urodynamic profiles are diagnosed with BOO without DU. However, the possibility of BOO is often neglected in women with DU-like (low-pressure low-flow) urodynamic (UDS) profiles. By reviewing the videourodynamic studies (VUDS) of 1678 women, our study identified the key factors suggesting urodynamic BOO (determined by radiographic evidence of obstruction) in women with DU-like UDS profiles (Pdet.Qmax < 20 cmH2O and Qmax < 15 mL/s). In 355 women with DU-like UDS profiles, there were 70 (19.7%) with BOO and 285 (80.3%) without BOO. The BOO group had predominantly obstructive symptoms. The BOO group showed significantly decreased bladder sensation, lower detrusor pressure (Pdet.Qmax), lower flow rate (Qmax), smaller voided volume, and larger post-voiding residual (PVR) compared to the non-BOO group. In multivariate analysis, volume at first sensation, Qmax, PVR, and detrusor overactivity (DO) remained independent factors for BOO. The receiver operating characteristic (ROC) areas for the parameters were largest for PVR (area = 0.786) and Qmax (area = 0.742). The best cut-off points were 220 mL for PVR and 4 mL/s for Qmax. Our findings provide simple indicators for BOO in women with DU.Po-Ming ChowSheng-Mou HsiaoHann-Chorng KuoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Po-Ming Chow Sheng-Mou Hsiao Hann-Chorng Kuo Identifying occult bladder outlet obstruction in women with detrusor-underactivity-like urodynamic profiles
description	Abstract Voiding dysfunction can result from detrusor underactivity (DU), bladder outlet obstruction (BOO), or both. Conceptually, women with high-pressure low-flow urodynamic profiles are diagnosed with BOO without DU. However, the possibility of BOO is often neglected in women with DU-like (low-pressure low-flow) urodynamic (UDS) profiles. By reviewing the videourodynamic studies (VUDS) of 1678 women, our study identified the key factors suggesting urodynamic BOO (determined by radiographic evidence of obstruction) in women with DU-like UDS profiles (Pdet.Qmax < 20 cmH2O and Qmax < 15 mL/s). In 355 women with DU-like UDS profiles, there were 70 (19.7%) with BOO and 285 (80.3%) without BOO. The BOO group had predominantly obstructive symptoms. The BOO group showed significantly decreased bladder sensation, lower detrusor pressure (Pdet.Qmax), lower flow rate (Qmax), smaller voided volume, and larger post-voiding residual (PVR) compared to the non-BOO group. In multivariate analysis, volume at first sensation, Qmax, PVR, and detrusor overactivity (DO) remained independent factors for BOO. The receiver operating characteristic (ROC) areas for the parameters were largest for PVR (area = 0.786) and Qmax (area = 0.742). The best cut-off points were 220 mL for PVR and 4 mL/s for Qmax. Our findings provide simple indicators for BOO in women with DU.
format	article
author	Po-Ming Chow Sheng-Mou Hsiao Hann-Chorng Kuo
author_facet	Po-Ming Chow Sheng-Mou Hsiao Hann-Chorng Kuo
author_sort	Po-Ming Chow
title	Identifying occult bladder outlet obstruction in women with detrusor-underactivity-like urodynamic profiles
title_short	Identifying occult bladder outlet obstruction in women with detrusor-underactivity-like urodynamic profiles
title_full	Identifying occult bladder outlet obstruction in women with detrusor-underactivity-like urodynamic profiles
title_fullStr	Identifying occult bladder outlet obstruction in women with detrusor-underactivity-like urodynamic profiles
title_full_unstemmed	Identifying occult bladder outlet obstruction in women with detrusor-underactivity-like urodynamic profiles
title_sort	identifying occult bladder outlet obstruction in women with detrusor-underactivity-like urodynamic profiles
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/cd57e7ad04344a78868d555d68941a70
work_keys_str_mv	AT pomingchow identifyingoccultbladderoutletobstructioninwomenwithdetrusorunderactivitylikeurodynamicprofiles AT shengmouhsiao identifyingoccultbladderoutletobstructioninwomenwithdetrusorunderactivitylikeurodynamicprofiles AT hannchorngkuo identifyingoccultbladderoutletobstructioninwomenwithdetrusorunderactivitylikeurodynamicprofiles
_version_	1718372161254588416

Identifying occult bladder outlet obstruction in women with detrusor-underactivity-like urodynamic profiles

Ejemplares similares