Diagnostic Efficacy of Endometrial Aspiration Cytology in Abnormal Uterine Bleeding - A Cross Sectional Study at a Tertiary Care Hospital

Background: Application of cytology in evaluation of endometrial lesions is emerging and is a valuable diagnostic tool which includes endometrial aspiration cytology and imprint cytology. This study was conducted to analyze the morphological patterns of endometrium in abnormal uterine bleeding by en...

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Autores principales: Amita Kumari, Amita K
Formato: article
Lenguaje:EN
Publicado: Light House Polyclinic Mangalore 2021
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Acceso en línea:https://doaj.org/article/cd5b00f755f743c3b95f95be5ea793e1
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spelling oai:doaj.org-article:cd5b00f755f743c3b95f95be5ea793e12021-11-12T08:53:35ZDiagnostic Efficacy of Endometrial Aspiration Cytology in Abnormal Uterine Bleeding - A Cross Sectional Study at a Tertiary Care Hospital0972-5997https://doaj.org/article/cd5b00f755f743c3b95f95be5ea793e12021-10-01T00:00:00Zhttps://www.ojhas.org/issue79/2021-3-13.htmlhttps://doaj.org/toc/0972-5997Background: Application of cytology in evaluation of endometrial lesions is emerging and is a valuable diagnostic tool which includes endometrial aspiration cytology and imprint cytology. This study was conducted to analyze the morphological patterns of endometrium in abnormal uterine bleeding by endometrium aspiration cytology and to compare its diagnostic efficacy of with histopathology. Material and method: This was a prospective analytical study which included 127 cases with abnormal uterine bleeding. Aspiration was done using nasogastric tube. This was followed by dilatation and curettage, material obtained and serial imprints were taken. The endometrial biopsy was then sent for histopathological examination. The aspirates and biopsy were stained appropriately. Cytomorphology was studied and subsequently correlated with histopathological features. Results: Mean age was 41.57 ± 8.42 years and menorrhagia was the most common pattern of bleeding. The most common endometrial pattern observed was of cyclic endometrium by both the techniques. The sensitivity, specificity, positive predictive value and negative predictive value of endometrial aspiration cytology in diagnosing malignancy was 66.67%, 100%, 100% and 99.07% respectively. Conclusion: Endometrial cytology is a simple, rapid, safe and cost-effective tool in evaluating abnormal uterine bleeding in identification of specific pathology. Pathologist must be aware of the cytomorphology and potential pitfalls especially in distinction of atypical hyperplasia and grade 1 adenocarcinomas to improve diagnostic accuracy.Amita KumariAmita KLight House Polyclinic Mangalore articleendometrial aspiration cytologycyclic endometriumadenocarcinomahistopathology.MedicineRENOnline Journal of Health & Allied Sciences, Vol 20, Iss 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic endometrial aspiration cytology
cyclic endometrium
adenocarcinoma
histopathology.
Medicine
R
spellingShingle endometrial aspiration cytology
cyclic endometrium
adenocarcinoma
histopathology.
Medicine
R
Amita Kumari
Amita K
Diagnostic Efficacy of Endometrial Aspiration Cytology in Abnormal Uterine Bleeding - A Cross Sectional Study at a Tertiary Care Hospital
description Background: Application of cytology in evaluation of endometrial lesions is emerging and is a valuable diagnostic tool which includes endometrial aspiration cytology and imprint cytology. This study was conducted to analyze the morphological patterns of endometrium in abnormal uterine bleeding by endometrium aspiration cytology and to compare its diagnostic efficacy of with histopathology. Material and method: This was a prospective analytical study which included 127 cases with abnormal uterine bleeding. Aspiration was done using nasogastric tube. This was followed by dilatation and curettage, material obtained and serial imprints were taken. The endometrial biopsy was then sent for histopathological examination. The aspirates and biopsy were stained appropriately. Cytomorphology was studied and subsequently correlated with histopathological features. Results: Mean age was 41.57 ± 8.42 years and menorrhagia was the most common pattern of bleeding. The most common endometrial pattern observed was of cyclic endometrium by both the techniques. The sensitivity, specificity, positive predictive value and negative predictive value of endometrial aspiration cytology in diagnosing malignancy was 66.67%, 100%, 100% and 99.07% respectively. Conclusion: Endometrial cytology is a simple, rapid, safe and cost-effective tool in evaluating abnormal uterine bleeding in identification of specific pathology. Pathologist must be aware of the cytomorphology and potential pitfalls especially in distinction of atypical hyperplasia and grade 1 adenocarcinomas to improve diagnostic accuracy.
format article
author Amita Kumari
Amita K
author_facet Amita Kumari
Amita K
author_sort Amita Kumari
title Diagnostic Efficacy of Endometrial Aspiration Cytology in Abnormal Uterine Bleeding - A Cross Sectional Study at a Tertiary Care Hospital
title_short Diagnostic Efficacy of Endometrial Aspiration Cytology in Abnormal Uterine Bleeding - A Cross Sectional Study at a Tertiary Care Hospital
title_full Diagnostic Efficacy of Endometrial Aspiration Cytology in Abnormal Uterine Bleeding - A Cross Sectional Study at a Tertiary Care Hospital
title_fullStr Diagnostic Efficacy of Endometrial Aspiration Cytology in Abnormal Uterine Bleeding - A Cross Sectional Study at a Tertiary Care Hospital
title_full_unstemmed Diagnostic Efficacy of Endometrial Aspiration Cytology in Abnormal Uterine Bleeding - A Cross Sectional Study at a Tertiary Care Hospital
title_sort diagnostic efficacy of endometrial aspiration cytology in abnormal uterine bleeding - a cross sectional study at a tertiary care hospital
publisher Light House Polyclinic Mangalore
publishDate 2021
url https://doaj.org/article/cd5b00f755f743c3b95f95be5ea793e1
work_keys_str_mv AT amitakumari diagnosticefficacyofendometrialaspirationcytologyinabnormaluterinebleedingacrosssectionalstudyatatertiarycarehospital
AT amitak diagnosticefficacyofendometrialaspirationcytologyinabnormaluterinebleedingacrosssectionalstudyatatertiarycarehospital
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