CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves

Myelinating cells differentially myelinate axons of different diameters, however whether they can also restrict radial axonal growth remained unclear. Here, the authors show that CMTM6 in Schwann cells restricts axon diameters, affecting sensory nerve conduction and behavioral performance.

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Autores principales:	Maria A. Eichel, Vasiliki-Ilya Gargareta, Elisa D’Este, Robert Fledrich, Theresa Kungl, Tobias J. Buscham, Katja A. Lüders, Cristina Miracle, Ramona B. Jung, Ute Distler, Kathrin Kusch, Wiebke Möbius, Swen Hülsmann, Stefan Tenzer, Klaus-Armin Nave, Hauke B. Werner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cd5b24a40b18428fa39de773cdde5765
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spelling	oai:doaj.org-article:cd5b24a40b18428fa39de773cdde57652021-12-02T17:19:40ZCMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves10.1038/s41467-020-18172-72041-1723https://doaj.org/article/cd5b24a40b18428fa39de773cdde57652020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18172-7https://doaj.org/toc/2041-1723Myelinating cells differentially myelinate axons of different diameters, however whether they can also restrict radial axonal growth remained unclear. Here, the authors show that CMTM6 in Schwann cells restricts axon diameters, affecting sensory nerve conduction and behavioral performance.Maria A. EichelVasiliki-Ilya GargaretaElisa D’EsteRobert FledrichTheresa KunglTobias J. BuschamKatja A. LüdersCristina MiracleRamona B. JungUte DistlerKathrin KuschWiebke MöbiusSwen HülsmannStefan TenzerKlaus-Armin NaveHauke B. WernerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maria A. Eichel Vasiliki-Ilya Gargareta Elisa D’Este Robert Fledrich Theresa Kungl Tobias J. Buscham Katja A. Lüders Cristina Miracle Ramona B. Jung Ute Distler Kathrin Kusch Wiebke Möbius Swen Hülsmann Stefan Tenzer Klaus-Armin Nave Hauke B. Werner CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves
description	Myelinating cells differentially myelinate axons of different diameters, however whether they can also restrict radial axonal growth remained unclear. Here, the authors show that CMTM6 in Schwann cells restricts axon diameters, affecting sensory nerve conduction and behavioral performance.
format	article
author	Maria A. Eichel Vasiliki-Ilya Gargareta Elisa D’Este Robert Fledrich Theresa Kungl Tobias J. Buscham Katja A. Lüders Cristina Miracle Ramona B. Jung Ute Distler Kathrin Kusch Wiebke Möbius Swen Hülsmann Stefan Tenzer Klaus-Armin Nave Hauke B. Werner
author_facet	Maria A. Eichel Vasiliki-Ilya Gargareta Elisa D’Este Robert Fledrich Theresa Kungl Tobias J. Buscham Katja A. Lüders Cristina Miracle Ramona B. Jung Ute Distler Kathrin Kusch Wiebke Möbius Swen Hülsmann Stefan Tenzer Klaus-Armin Nave Hauke B. Werner
author_sort	Maria A. Eichel
title	CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves
title_short	CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves
title_full	CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves
title_fullStr	CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves
title_full_unstemmed	CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves
title_sort	cmtm6 expressed on the adaxonal schwann cell surface restricts axonal diameters in peripheral nerves
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/cd5b24a40b18428fa39de773cdde5765
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CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves

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