Non-Alcoholic Fatty Liver Disease as a Risk for Colorectal Cancer Development and the Role of Screening Colonoscopy in Clinical Practice

Colorectal cancer (CRC) is still the third mostcommoncancer in the world, which is the fourth cause of cancer-related mortality. It iscaused either due to strong genetic factors such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colon cancerorduetomodifiedmetabolic factors suc...

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Autores principales: Cosmas Rinaldi Adithya Lesmana, Mutiara Lirendra, Laurentius Adrianto Lesmana
Formato: article
Lenguaje:EN
Publicado: Shiraz University of Medical Sciences 2019
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Acceso en línea:https://doaj.org/article/cd6083b6d5094d0aab267bc8a08a2958
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spelling oai:doaj.org-article:cd6083b6d5094d0aab267bc8a08a29582021-11-14T08:42:11ZNon-Alcoholic Fatty Liver Disease as a Risk for Colorectal Cancer Development and the Role of Screening Colonoscopy in Clinical Practice2783-2430https://doaj.org/article/cd6083b6d5094d0aab267bc8a08a29582019-03-01T00:00:00Zhttps://colorectalresearch.sums.ac.ir/article_47191_b1742a52f7657fefd2c23457a0e4671d.pdfhttps://doaj.org/toc/2783-2430Colorectal cancer (CRC) is still the third mostcommoncancer in the world, which is the fourth cause of cancer-related mortality. It iscaused either due to strong genetic factors such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colon cancerorduetomodifiedmetabolic factors such as obesityanddiabetes, whichrepresents insulin resistance condition. Non-alcoholic fattyliver disease (NAFLD) is increasing not only inWestern countries but also in Asian countries. This disease has been included in themetabolic disease family such as diabetes, hypertension, obesity, and dyslipidemia. Some studies have shown that there is a strongassociation between NAFLD and the risk of CRC development through the presence of an adenomatous polyp. However, there iscurrently no consensus on whether routine screening colonoscopy should be done in all NAFLD patients with respects to its costand invasiveness.Cosmas Rinaldi Adithya LesmanaMutiara LirendraLaurentius Adrianto LesmanaShiraz University of Medical Sciencesarticlenon-alcoholic fatty liver diseasecolorectal cancercolonoscopyMedicineRENIranian Journal of Colorectal Research, Vol 7, Iss 1 (2019)
institution DOAJ
collection DOAJ
language EN
topic non-alcoholic fatty liver disease
colorectal cancer
colonoscopy
Medicine
R
spellingShingle non-alcoholic fatty liver disease
colorectal cancer
colonoscopy
Medicine
R
Cosmas Rinaldi Adithya Lesmana
Mutiara Lirendra
Laurentius Adrianto Lesmana
Non-Alcoholic Fatty Liver Disease as a Risk for Colorectal Cancer Development and the Role of Screening Colonoscopy in Clinical Practice
description Colorectal cancer (CRC) is still the third mostcommoncancer in the world, which is the fourth cause of cancer-related mortality. It iscaused either due to strong genetic factors such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colon cancerorduetomodifiedmetabolic factors such as obesityanddiabetes, whichrepresents insulin resistance condition. Non-alcoholic fattyliver disease (NAFLD) is increasing not only inWestern countries but also in Asian countries. This disease has been included in themetabolic disease family such as diabetes, hypertension, obesity, and dyslipidemia. Some studies have shown that there is a strongassociation between NAFLD and the risk of CRC development through the presence of an adenomatous polyp. However, there iscurrently no consensus on whether routine screening colonoscopy should be done in all NAFLD patients with respects to its costand invasiveness.
format article
author Cosmas Rinaldi Adithya Lesmana
Mutiara Lirendra
Laurentius Adrianto Lesmana
author_facet Cosmas Rinaldi Adithya Lesmana
Mutiara Lirendra
Laurentius Adrianto Lesmana
author_sort Cosmas Rinaldi Adithya Lesmana
title Non-Alcoholic Fatty Liver Disease as a Risk for Colorectal Cancer Development and the Role of Screening Colonoscopy in Clinical Practice
title_short Non-Alcoholic Fatty Liver Disease as a Risk for Colorectal Cancer Development and the Role of Screening Colonoscopy in Clinical Practice
title_full Non-Alcoholic Fatty Liver Disease as a Risk for Colorectal Cancer Development and the Role of Screening Colonoscopy in Clinical Practice
title_fullStr Non-Alcoholic Fatty Liver Disease as a Risk for Colorectal Cancer Development and the Role of Screening Colonoscopy in Clinical Practice
title_full_unstemmed Non-Alcoholic Fatty Liver Disease as a Risk for Colorectal Cancer Development and the Role of Screening Colonoscopy in Clinical Practice
title_sort non-alcoholic fatty liver disease as a risk for colorectal cancer development and the role of screening colonoscopy in clinical practice
publisher Shiraz University of Medical Sciences
publishDate 2019
url https://doaj.org/article/cd6083b6d5094d0aab267bc8a08a2958
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AT mutiaralirendra nonalcoholicfattyliverdiseaseasariskforcolorectalcancerdevelopmentandtheroleofscreeningcolonoscopyinclinicalpractice
AT laurentiusadriantolesmana nonalcoholicfattyliverdiseaseasariskforcolorectalcancerdevelopmentandtheroleofscreeningcolonoscopyinclinicalpractice
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