Data-Driven Analysis of Fluorination of Ligands of Aminergic G Protein Coupled Receptors
Currently, G protein-coupled receptors are the targets with the highest number of drugs in many therapeutic areas. Fluorination has become a common strategy in designing highly active biological compounds, as evidenced by the steadily increasing number of newly approved fluorine-containing drugs. He...
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Auteurs principaux: | Wojciech Pietruś, Rafał Kurczab, Dagmar Stumpfe, Andrzej J. Bojarski, Jürgen Bajorath |
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Format: | article |
Langue: | EN |
Publié: |
MDPI AG
2021
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Accès en ligne: | https://doaj.org/article/cd62e2b920104ecb91d770b5e194e417 |
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