Data-Driven Analysis of Fluorination of Ligands of Aminergic G Protein Coupled Receptors

Currently, G protein-coupled receptors are the targets with the highest number of drugs in many therapeutic areas. Fluorination has become a common strategy in designing highly active biological compounds, as evidenced by the steadily increasing number of newly approved fluorine-containing drugs. He...

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Autores principales: Wojciech Pietruś, Rafał Kurczab, Dagmar Stumpfe, Andrzej J. Bojarski, Jürgen Bajorath
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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MMP
Acceso en línea:https://doaj.org/article/cd62e2b920104ecb91d770b5e194e417
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