Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks

Microbial rhodopsins can be used to control action potentials, while animal opsins can be used to control intracellular signaling pathways. The authors identify Opn7b as constitutively active Gi/o coupled receptor that can be deactivated by light and used to modulate neuronal activity.

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Autores principales:	Raziye Karapinar, Jan Claudius Schwitalla, Dennis Eickelbeck, Johanna Pakusch, Brix Mücher, Michelle Grömmke, Tatjana Surdin, Thomas Knöpfel, Melanie D. Mark, Ida Siveke, Stefan Herlitze
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cd6b728c8c2a41f6902c7cf1ab408a53
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spelling	oai:doaj.org-article:cd6b728c8c2a41f6902c7cf1ab408a532021-12-02T16:17:59ZReverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks10.1038/s41467-021-24718-02041-1723https://doaj.org/article/cd6b728c8c2a41f6902c7cf1ab408a532021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24718-0https://doaj.org/toc/2041-1723Microbial rhodopsins can be used to control action potentials, while animal opsins can be used to control intracellular signaling pathways. The authors identify Opn7b as constitutively active Gi/o coupled receptor that can be deactivated by light and used to modulate neuronal activity.Raziye KarapinarJan Claudius SchwitallaDennis EickelbeckJohanna PakuschBrix MücherMichelle GrömmkeTatjana SurdinThomas KnöpfelMelanie D. MarkIda SivekeStefan HerlitzeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Raziye Karapinar Jan Claudius Schwitalla Dennis Eickelbeck Johanna Pakusch Brix Mücher Michelle Grömmke Tatjana Surdin Thomas Knöpfel Melanie D. Mark Ida Siveke Stefan Herlitze Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks
description	Microbial rhodopsins can be used to control action potentials, while animal opsins can be used to control intracellular signaling pathways. The authors identify Opn7b as constitutively active Gi/o coupled receptor that can be deactivated by light and used to modulate neuronal activity.
format	article
author	Raziye Karapinar Jan Claudius Schwitalla Dennis Eickelbeck Johanna Pakusch Brix Mücher Michelle Grömmke Tatjana Surdin Thomas Knöpfel Melanie D. Mark Ida Siveke Stefan Herlitze
author_facet	Raziye Karapinar Jan Claudius Schwitalla Dennis Eickelbeck Johanna Pakusch Brix Mücher Michelle Grömmke Tatjana Surdin Thomas Knöpfel Melanie D. Mark Ida Siveke Stefan Herlitze
author_sort	Raziye Karapinar
title	Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks
title_short	Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks
title_full	Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks
title_fullStr	Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks
title_full_unstemmed	Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks
title_sort	reverse optogenetics of g protein signaling by zebrafish non-visual opsin opn7b for synchronization of neuronal networks
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/cd6b728c8c2a41f6902c7cf1ab408a53
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Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks

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