A Case of Rhupus with Rowell Syndrome

Abdulrahman Y Almansouri,1 Zeyad A Alzahrani2 1Department of Medicine, King Abdulaziz Medical City, Ministry of National Guard - Health Affairs, Jeddah, Saudi Arabia; 2Division of Rheumatology, Department of Medicine, King Abdulaziz Medical City, Ministry of National Guard - Health Affairs, Jeddah,...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Almansouri AY, Alzahrani ZA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	rowell syndrome- systemic lupus erythematosus- erythema multiform- cutaneous lupus erythematosus- rheumatoid arthritis. Diseases of the musculoskeletal system RC925-935
Acceso en línea:	https://doaj.org/article/cd6cb884df4e454db1f73ec957927419
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:cd6cb884df4e454db1f73ec957927419
record_format	dspace
spelling	oai:doaj.org-article:cd6cb884df4e454db1f73ec9579274192021-12-02T09:31:09ZA Case of Rhupus with Rowell Syndrome1179-156Xhttps://doaj.org/article/cd6cb884df4e454db1f73ec9579274192020-06-01T00:00:00Zhttps://www.dovepress.com/a-case-of-rhupus-with-rowell-syndrome-peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156XAbdulrahman Y Almansouri,1 Zeyad A Alzahrani2 1Department of Medicine, King Abdulaziz Medical City, Ministry of National Guard - Health Affairs, Jeddah, Saudi Arabia; 2Division of Rheumatology, Department of Medicine, King Abdulaziz Medical City, Ministry of National Guard - Health Affairs, Jeddah, Saudi ArabiaCorrespondence: Abdulrahman Y Almansouri P.O. Box 7194, Jeddah 21462, Saudi ArabiaTel +966 565656486Email red.amlor@gmail.comAbstract: We report a case of 30-year-old female who presented initially with hair loss, photosensitive malar rash, morning stiffness and synovitis. She was diagnosed with Rhupus syndrome based on clinical and laboratory findings. Few months after starting hydroxychloroquine, esomeprazole and azathioprine, and failing methotrexate (because of erosive pill-induced esophagitis), she presented with generalized maculopapular dusky reddish rash in her body, back and extremities. Her anti-double stranded-DNA, anti-nuclear antibody, anti-Ro/SSA and anti-La/SSB were positive. Anti-cyclic citrullinated peptide antibody was moderately positive. She had low complements: C3 and C4. Herpes simplex IgM and mycoplasma tested negative. Skin biopsy from right arm showed evidence of erythema multiform. She met the criteria for the diagnosis of Rowell syndrome. We managed her with hydroxychloroquine, prednisolone, mycophenolate mofetil and topical agents and discontinued esomeprazole. We also review the management of Rowell syndrome in the literature.Keywords: Rowell syndrome, systemic lupus erythematosus, erythema multiform, cutaneous lupus erythematosus, rheumatoid arthritis  Almansouri AYAlzahrani ZADove Medical Pressarticlerowell syndrome- systemic lupus erythematosus- erythema multiform- cutaneous lupus erythematosus- rheumatoid arthritis.Diseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol Volume 12, Pp 91-96 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	rowell syndrome- systemic lupus erythematosus- erythema multiform- cutaneous lupus erythematosus- rheumatoid arthritis. Diseases of the musculoskeletal system RC925-935
spellingShingle	rowell syndrome- systemic lupus erythematosus- erythema multiform- cutaneous lupus erythematosus- rheumatoid arthritis. Diseases of the musculoskeletal system RC925-935 Almansouri AY Alzahrani ZA A Case of Rhupus with Rowell Syndrome
description	Abdulrahman Y Almansouri,1 Zeyad A Alzahrani2 1Department of Medicine, King Abdulaziz Medical City, Ministry of National Guard - Health Affairs, Jeddah, Saudi Arabia; 2Division of Rheumatology, Department of Medicine, King Abdulaziz Medical City, Ministry of National Guard - Health Affairs, Jeddah, Saudi ArabiaCorrespondence: Abdulrahman Y Almansouri P.O. Box 7194, Jeddah 21462, Saudi ArabiaTel +966 565656486Email red.amlor@gmail.comAbstract: We report a case of 30-year-old female who presented initially with hair loss, photosensitive malar rash, morning stiffness and synovitis. She was diagnosed with Rhupus syndrome based on clinical and laboratory findings. Few months after starting hydroxychloroquine, esomeprazole and azathioprine, and failing methotrexate (because of erosive pill-induced esophagitis), she presented with generalized maculopapular dusky reddish rash in her body, back and extremities. Her anti-double stranded-DNA, anti-nuclear antibody, anti-Ro/SSA and anti-La/SSB were positive. Anti-cyclic citrullinated peptide antibody was moderately positive. She had low complements: C3 and C4. Herpes simplex IgM and mycoplasma tested negative. Skin biopsy from right arm showed evidence of erythema multiform. She met the criteria for the diagnosis of Rowell syndrome. We managed her with hydroxychloroquine, prednisolone, mycophenolate mofetil and topical agents and discontinued esomeprazole. We also review the management of Rowell syndrome in the literature.Keywords: Rowell syndrome, systemic lupus erythematosus, erythema multiform, cutaneous lupus erythematosus, rheumatoid arthritis
format	article
author	Almansouri AY Alzahrani ZA
author_facet	Almansouri AY Alzahrani ZA
author_sort	Almansouri AY
title	A Case of Rhupus with Rowell Syndrome
title_short	A Case of Rhupus with Rowell Syndrome
title_full	A Case of Rhupus with Rowell Syndrome
title_fullStr	A Case of Rhupus with Rowell Syndrome
title_full_unstemmed	A Case of Rhupus with Rowell Syndrome
title_sort	case of rhupus with rowell syndrome
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/cd6cb884df4e454db1f73ec957927419
work_keys_str_mv	AT almansouriay acaseofrhupuswithrowellsyndrome AT alzahraniza acaseofrhupuswithrowellsyndrome AT almansouriay caseofrhupuswithrowellsyndrome AT alzahraniza caseofrhupuswithrowellsyndrome
_version_	1718398090112663552

A Case of Rhupus with Rowell Syndrome

Ejemplares similares