Measurement of peripapillary retinal nerve fiber layer thickness and macular thickness in anisometropia using spectral domain optical coherence tomography: a prospective study

Neha Singh, Jolly Rohatgi, Ved Prakash Gupta, Vinod Kumar Department of Ophthalmology, University College of Medical Sciences, Delhi, India Purpose: To study whether there is a difference in central macular thickness (CMT) and peripapillary retinal nerve fiber layer (RNFL) thickness between the tw...

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Autores principales:	Singh N, Rohatgi J, Gupta VP, Kumar V
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	RNFL thickness CMT Anisometropia Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/cd6fa18f0fe44799a408ca2be70cd936
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spelling	oai:doaj.org-article:cd6fa18f0fe44799a408ca2be70cd9362021-12-02T04:16:07ZMeasurement of peripapillary retinal nerve fiber layer thickness and macular thickness in anisometropia using spectral domain optical coherence tomography: a prospective study1177-5483https://doaj.org/article/cd6fa18f0fe44799a408ca2be70cd9362017-02-01T00:00:00Zhttps://www.dovepress.com/measurement-of-peripapillary-retinal-nerve-fiber-layer-thickness-and-m-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Neha Singh, Jolly Rohatgi, Ved Prakash Gupta, Vinod Kumar Department of Ophthalmology, University College of Medical Sciences, Delhi, India Purpose: To study whether there is a difference in central macular thickness (CMT) and peripapillary retinal nerve fiber layer (RNFL) thickness between the two eyes of individuals having anisometropia >1 diopter (D) using spectral domain optical coherence tomography (OCT).Material and methods: One hundred and one subjects, 31 with myopic anisometropia, 28 with astigmatic anisometropia, and 42 with hypermetropic anisometropia, were enrolled in the study. After informed consent, detailed ophthalmological examination was performed for every patient including cycloplegic refraction, best corrected visual acuity, slit lamp, and fundus examination. After routine ophthalmic examination peripapillary RNFL and CMT were measured using spectral domain OCT and the values of the two eyes were compared in the three types of anisometropia. Axial length was measured using an A Scan ultrasound biometer (Appa Scan-2000).Results: The average age of subjects was 21.7±9.3 years. The mean anisometropia was 3.11±1.7 D in myopia; 2±0.99 D in astigmatism; and 3.68±1.85 D in hypermetropia. There was a statistically significant difference in axial length of the worse and better eye in both myopic and hypermetropic anisometropia (P=0.00). There was no significant difference between CMT of better and worse eyes in anisomyopia (P=0.79), anisohypermetropia (P=0.09), or anisoastigmatism (P=0.16). In anisohypermetropia only inferior quadrant RNFL was found to be significantly thicker (P=0.011) in eyes with greater refractive error.Conclusion: There does not appear to be a significant difference in CMT and peripapillary RNFL thickness in anisomyopia and anisoastigmatism. However, in anisohypermetropia inferior quadrant RNFL was found to be significantly thicker. Keywords: RNFL, CMT, anisometropia, amblyopiaSingh NRohatgi JGupta VPKumar VDove Medical PressarticleRNFL thicknessCMTAnisometropiaOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 11, Pp 429-434 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	RNFL thickness CMT Anisometropia Ophthalmology RE1-994
spellingShingle	RNFL thickness CMT Anisometropia Ophthalmology RE1-994 Singh N Rohatgi J Gupta VP Kumar V Measurement of peripapillary retinal nerve fiber layer thickness and macular thickness in anisometropia using spectral domain optical coherence tomography: a prospective study
description	Neha Singh, Jolly Rohatgi, Ved Prakash Gupta, Vinod Kumar Department of Ophthalmology, University College of Medical Sciences, Delhi, India Purpose: To study whether there is a difference in central macular thickness (CMT) and peripapillary retinal nerve fiber layer (RNFL) thickness between the two eyes of individuals having anisometropia >1 diopter (D) using spectral domain optical coherence tomography (OCT).Material and methods: One hundred and one subjects, 31 with myopic anisometropia, 28 with astigmatic anisometropia, and 42 with hypermetropic anisometropia, were enrolled in the study. After informed consent, detailed ophthalmological examination was performed for every patient including cycloplegic refraction, best corrected visual acuity, slit lamp, and fundus examination. After routine ophthalmic examination peripapillary RNFL and CMT were measured using spectral domain OCT and the values of the two eyes were compared in the three types of anisometropia. Axial length was measured using an A Scan ultrasound biometer (Appa Scan-2000).Results: The average age of subjects was 21.7±9.3 years. The mean anisometropia was 3.11±1.7 D in myopia; 2±0.99 D in astigmatism; and 3.68±1.85 D in hypermetropia. There was a statistically significant difference in axial length of the worse and better eye in both myopic and hypermetropic anisometropia (P=0.00). There was no significant difference between CMT of better and worse eyes in anisomyopia (P=0.79), anisohypermetropia (P=0.09), or anisoastigmatism (P=0.16). In anisohypermetropia only inferior quadrant RNFL was found to be significantly thicker (P=0.011) in eyes with greater refractive error.Conclusion: There does not appear to be a significant difference in CMT and peripapillary RNFL thickness in anisomyopia and anisoastigmatism. However, in anisohypermetropia inferior quadrant RNFL was found to be significantly thicker. Keywords: RNFL, CMT, anisometropia, amblyopia
format	article
author	Singh N Rohatgi J Gupta VP Kumar V
author_facet	Singh N Rohatgi J Gupta VP Kumar V
author_sort	Singh N
title	Measurement of peripapillary retinal nerve fiber layer thickness and macular thickness in anisometropia using spectral domain optical coherence tomography: a prospective study
title_short	Measurement of peripapillary retinal nerve fiber layer thickness and macular thickness in anisometropia using spectral domain optical coherence tomography: a prospective study
title_full	Measurement of peripapillary retinal nerve fiber layer thickness and macular thickness in anisometropia using spectral domain optical coherence tomography: a prospective study
title_fullStr	Measurement of peripapillary retinal nerve fiber layer thickness and macular thickness in anisometropia using spectral domain optical coherence tomography: a prospective study
title_full_unstemmed	Measurement of peripapillary retinal nerve fiber layer thickness and macular thickness in anisometropia using spectral domain optical coherence tomography: a prospective study
title_sort	measurement of peripapillary retinal nerve fiber layer thickness and macular thickness in anisometropia using spectral domain optical coherence tomography: a prospective study
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/cd6fa18f0fe44799a408ca2be70cd936
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Measurement of peripapillary retinal nerve fiber layer thickness and macular thickness in anisometropia using spectral domain optical coherence tomography: a prospective study

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