Portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals

Bioluminescence imaging tends to rely on transgenic luciferase-expressing cells and animals. Here the authors report a portable bioluminescent system to non-invasively measure intra- and extracellular enzymes in vivo in non-transgenic animals which do not express luciferase.

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Detalles Bibliográficos
Autores principales: Aleksey Yevtodiyenko, Arkadiy Bazhin, Pavlo Khodakivskyi, Aurelien Godinat, Ghyslain Budin, Tamara Maric, Giorgio Pietramaggiori, Sandra S. Scherer, Marina Kunchulia, George Eppeldauer, Sergey V. Polyakov, Kevin P. Francis, Jeffrey N. Bryan, Elena A. Goun
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/cd73326c35744d1ea4308c3e175f26b0
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Sumario:Bioluminescence imaging tends to rely on transgenic luciferase-expressing cells and animals. Here the authors report a portable bioluminescent system to non-invasively measure intra- and extracellular enzymes in vivo in non-transgenic animals which do not express luciferase.