Portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals

Bioluminescence imaging tends to rely on transgenic luciferase-expressing cells and animals. Here the authors report a portable bioluminescent system to non-invasively measure intra- and extracellular enzymes in vivo in non-transgenic animals which do not express luciferase.

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Autores principales:	Aleksey Yevtodiyenko, Arkadiy Bazhin, Pavlo Khodakivskyi, Aurelien Godinat, Ghyslain Budin, Tamara Maric, Giorgio Pietramaggiori, Sandra S. Scherer, Marina Kunchulia, George Eppeldauer, Sergey V. Polyakov, Kevin P. Francis, Jeffrey N. Bryan, Elena A. Goun
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cd73326c35744d1ea4308c3e175f26b0
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spelling	oai:doaj.org-article:cd73326c35744d1ea4308c3e175f26b02021-12-02T17:02:04ZPortable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals10.1038/s41467-021-22892-92041-1723https://doaj.org/article/cd73326c35744d1ea4308c3e175f26b02021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22892-9https://doaj.org/toc/2041-1723Bioluminescence imaging tends to rely on transgenic luciferase-expressing cells and animals. Here the authors report a portable bioluminescent system to non-invasively measure intra- and extracellular enzymes in vivo in non-transgenic animals which do not express luciferase.Aleksey YevtodiyenkoArkadiy BazhinPavlo KhodakivskyiAurelien GodinatGhyslain BudinTamara MaricGiorgio PietramaggioriSandra S. SchererMarina KunchuliaGeorge EppeldauerSergey V. PolyakovKevin P. FrancisJeffrey N. BryanElena A. GounNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aleksey Yevtodiyenko Arkadiy Bazhin Pavlo Khodakivskyi Aurelien Godinat Ghyslain Budin Tamara Maric Giorgio Pietramaggiori Sandra S. Scherer Marina Kunchulia George Eppeldauer Sergey V. Polyakov Kevin P. Francis Jeffrey N. Bryan Elena A. Goun Portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals
description	Bioluminescence imaging tends to rely on transgenic luciferase-expressing cells and animals. Here the authors report a portable bioluminescent system to non-invasively measure intra- and extracellular enzymes in vivo in non-transgenic animals which do not express luciferase.
format	article
author	Aleksey Yevtodiyenko Arkadiy Bazhin Pavlo Khodakivskyi Aurelien Godinat Ghyslain Budin Tamara Maric Giorgio Pietramaggiori Sandra S. Scherer Marina Kunchulia George Eppeldauer Sergey V. Polyakov Kevin P. Francis Jeffrey N. Bryan Elena A. Goun
author_facet	Aleksey Yevtodiyenko Arkadiy Bazhin Pavlo Khodakivskyi Aurelien Godinat Ghyslain Budin Tamara Maric Giorgio Pietramaggiori Sandra S. Scherer Marina Kunchulia George Eppeldauer Sergey V. Polyakov Kevin P. Francis Jeffrey N. Bryan Elena A. Goun
author_sort	Aleksey Yevtodiyenko
title	Portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals
title_short	Portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals
title_full	Portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals
title_fullStr	Portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals
title_full_unstemmed	Portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals
title_sort	portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/cd73326c35744d1ea4308c3e175f26b0
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Portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals

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