Rodent Brain Pathology, Audiogenic Epilepsy

The review presents data which provides evidence for the internal relationship between the stages of rodent audiogenic seizures and post-ictal catalepsy with the general pattern of animal reaction to the dangerous stimuli and/or situation. The wild run stage of audiogenic seizure fit could be regard...

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Autores principales: Irina B. Fedotova, Natalia M. Surina, Georgy M. Nikolaev, Alexandre V. Revishchin, Inga I. Poletaeva
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/cd768a56585a4b7fab2c051e934e6a5c
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spelling oai:doaj.org-article:cd768a56585a4b7fab2c051e934e6a5c2021-11-25T16:50:00ZRodent Brain Pathology, Audiogenic Epilepsy10.3390/biomedicines91116412227-9059https://doaj.org/article/cd768a56585a4b7fab2c051e934e6a5c2021-11-01T00:00:00Zhttps://www.mdpi.com/2227-9059/9/11/1641https://doaj.org/toc/2227-9059The review presents data which provides evidence for the internal relationship between the stages of rodent audiogenic seizures and post-ictal catalepsy with the general pattern of animal reaction to the dangerous stimuli and/or situation. The wild run stage of audiogenic seizure fit could be regarded as an intense panic reaction, and this view found support in numerous experimental data. The phenomenon of audiogenic epilepsy probably attracted the attention of physiologists as rodents are extremely sensitive to dangerous sound stimuli. The seizure proneness in this group shares common physiological characteristics and depends on animal genotype. This concept could be the new platform for the study of epileptogenesis mechanisms.Irina B. FedotovaNatalia M. SurinaGeorgy M. NikolaevAlexandre V. RevishchinInga I. PoletaevaMDPI AGarticleaudiogenic epilepsyrodentsfear reactionbehavior geneticsBiology (General)QH301-705.5ENBiomedicines, Vol 9, Iss 1641, p 1641 (2021)
institution DOAJ
collection DOAJ
language EN
topic audiogenic epilepsy
rodents
fear reaction
behavior genetics
Biology (General)
QH301-705.5
spellingShingle audiogenic epilepsy
rodents
fear reaction
behavior genetics
Biology (General)
QH301-705.5
Irina B. Fedotova
Natalia M. Surina
Georgy M. Nikolaev
Alexandre V. Revishchin
Inga I. Poletaeva
Rodent Brain Pathology, Audiogenic Epilepsy
description The review presents data which provides evidence for the internal relationship between the stages of rodent audiogenic seizures and post-ictal catalepsy with the general pattern of animal reaction to the dangerous stimuli and/or situation. The wild run stage of audiogenic seizure fit could be regarded as an intense panic reaction, and this view found support in numerous experimental data. The phenomenon of audiogenic epilepsy probably attracted the attention of physiologists as rodents are extremely sensitive to dangerous sound stimuli. The seizure proneness in this group shares common physiological characteristics and depends on animal genotype. This concept could be the new platform for the study of epileptogenesis mechanisms.
format article
author Irina B. Fedotova
Natalia M. Surina
Georgy M. Nikolaev
Alexandre V. Revishchin
Inga I. Poletaeva
author_facet Irina B. Fedotova
Natalia M. Surina
Georgy M. Nikolaev
Alexandre V. Revishchin
Inga I. Poletaeva
author_sort Irina B. Fedotova
title Rodent Brain Pathology, Audiogenic Epilepsy
title_short Rodent Brain Pathology, Audiogenic Epilepsy
title_full Rodent Brain Pathology, Audiogenic Epilepsy
title_fullStr Rodent Brain Pathology, Audiogenic Epilepsy
title_full_unstemmed Rodent Brain Pathology, Audiogenic Epilepsy
title_sort rodent brain pathology, audiogenic epilepsy
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/cd768a56585a4b7fab2c051e934e6a5c
work_keys_str_mv AT irinabfedotova rodentbrainpathologyaudiogenicepilepsy
AT nataliamsurina rodentbrainpathologyaudiogenicepilepsy
AT georgymnikolaev rodentbrainpathologyaudiogenicepilepsy
AT alexandrevrevishchin rodentbrainpathologyaudiogenicepilepsy
AT ingaipoletaeva rodentbrainpathologyaudiogenicepilepsy
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