An Autocrine Negative Feedback Loop Inhibits Dictyostelium discoideum Proliferation through Pathways Including IP3/Ca <sup>2+</sup>
Many mammalian tissues such as the liver have the remarkable ability to regulate their size and have their cells stop proliferating when the tissue reaches the correct size. One possible mechanism involves the cells secreting a signal that they all sense, and a high level of the signal tells the ce...
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American Society for Microbiology
2021
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oai:doaj.org-article:cd769e08364847d297279543191a45c42021-11-03T21:15:04Z An Autocrine Negative Feedback Loop Inhibits Dictyostelium discoideum Proliferation through Pathways Including IP3/Ca <sup>2+</sup> 2150-751110.1128/mBio.01347-21https://doaj.org/article/cd769e08364847d297279543191a45c42021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01347-21https://doaj.org/toc/2150-7511 Many mammalian tissues such as the liver have the remarkable ability to regulate their size and have their cells stop proliferating when the tissue reaches the correct size. One possible mechanism involves the cells secreting a signal that they all sense, and a high level of the signal tells the cells that there are enough of them and to stop proliferating.Yu TangRamesh RijalDavid E. ZimmerhanzelJacquelyn R. McCulloughLouis A. CadenaRichard H. GomerAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Microbiology QR1-502 |
| spellingShingle |
Microbiology QR1-502 Yu Tang Ramesh Rijal David E. Zimmerhanzel Jacquelyn R. McCullough Louis A. Cadena Richard H. Gomer An Autocrine Negative Feedback Loop Inhibits Dictyostelium discoideum Proliferation through Pathways Including IP3/Ca <sup>2+</sup> |
| description |
Many mammalian tissues such as the liver have the remarkable ability to regulate their size and have their cells stop proliferating when the tissue reaches the correct size. One possible mechanism involves the cells secreting a signal that they all sense, and a high level of the signal tells the cells that there are enough of them and to stop proliferating. |
| format |
article |
| author |
Yu Tang Ramesh Rijal David E. Zimmerhanzel Jacquelyn R. McCullough Louis A. Cadena Richard H. Gomer |
| author_facet |
Yu Tang Ramesh Rijal David E. Zimmerhanzel Jacquelyn R. McCullough Louis A. Cadena Richard H. Gomer |
| author_sort |
Yu Tang |
| title |
An Autocrine Negative Feedback Loop Inhibits Dictyostelium discoideum Proliferation through Pathways Including IP3/Ca
<sup>2+</sup>
|
| title_short |
An Autocrine Negative Feedback Loop Inhibits Dictyostelium discoideum Proliferation through Pathways Including IP3/Ca
<sup>2+</sup>
|
| title_full |
An Autocrine Negative Feedback Loop Inhibits Dictyostelium discoideum Proliferation through Pathways Including IP3/Ca
<sup>2+</sup>
|
| title_fullStr |
An Autocrine Negative Feedback Loop Inhibits Dictyostelium discoideum Proliferation through Pathways Including IP3/Ca
<sup>2+</sup>
|
| title_full_unstemmed |
An Autocrine Negative Feedback Loop Inhibits Dictyostelium discoideum Proliferation through Pathways Including IP3/Ca
<sup>2+</sup>
|
| title_sort |
autocrine negative feedback loop inhibits dictyostelium discoideum proliferation through pathways including ip3/ca
<sup>2+</sup> |
| publisher |
American Society for Microbiology |
| publishDate |
2021 |
| url |
https://doaj.org/article/cd769e08364847d297279543191a45c4 |
| work_keys_str_mv |
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1718445424096837632 |