PfMDR1: mechanisms of transport modulation by functional polymorphisms.
ATP-Binding Cassette (ABC) transporters are efflux pumps frequently associated with multidrug resistance in many biological systems, including malaria. Antimalarial drug-resistance involves an ABC transporter, PfMDR1, a homologue of P-glycoprotein in humans. Twenty years of research have shown that...
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Auteurs principaux: | Pedro Eduardo Ferreira, Gabrielle Holmgren, Maria Isabel Veiga, Per Uhlén, Akira Kaneko, José Pedro Gil |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/cd80b8e866e44f16966a73e87bac27d6 |
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