PfMDR1: mechanisms of transport modulation by functional polymorphisms.

ATP-Binding Cassette (ABC) transporters are efflux pumps frequently associated with multidrug resistance in many biological systems, including malaria. Antimalarial drug-resistance involves an ABC transporter, PfMDR1, a homologue of P-glycoprotein in humans. Twenty years of research have shown that...

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Auteurs principaux: Pedro Eduardo Ferreira, Gabrielle Holmgren, Maria Isabel Veiga, Per Uhlén, Akira Kaneko, José Pedro Gil
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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Accès en ligne:https://doaj.org/article/cd80b8e866e44f16966a73e87bac27d6
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