The mobility limitation in healthy older people is due to weakness and not slower muscle contractile properties.

The maximal power generating capacity of a muscle declines with age and has a negative impact on the performance of daily life activities. As muscle power is the product of force and velocity, we recruited 20 young (10 men, 10 women: 20-31 years) and 20 older (10 men, 10 women: 65-86 years) people t...

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Autores principales:	Hans Degens, Julia Attias, Daniel Evans, Frederick Wilkins, Emma Hodson-Tole
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/cd88beaadb1740d288cd0568621c6ab5
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spelling	oai:doaj.org-article:cd88beaadb1740d288cd0568621c6ab52021-12-02T20:10:20ZThe mobility limitation in healthy older people is due to weakness and not slower muscle contractile properties.1932-620310.1371/journal.pone.0253531https://doaj.org/article/cd88beaadb1740d288cd0568621c6ab52021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0253531https://doaj.org/toc/1932-6203The maximal power generating capacity of a muscle declines with age and has a negative impact on the performance of daily life activities. As muscle power is the product of force and velocity, we recruited 20 young (10 men, 10 women: 20-31 years) and 20 older (10 men, 10 women: 65-86 years) people to investigate which of these components contributes to the lower power and performance in old age. After determination of the maximal isometric knee extension torque (MVC), they performed a countermovement jump (CMJ) in 1) the normal situation (normal), 2) with an extra load of 15% body weight (loaded) and 3) 15% lower body weight (unloaded with a pulley system), and a timed up-and-go test (TUG) in the normal or loaded condition. The TUG and CMJ performance was lower in old than young participants (p<0.001). Below a critical CMJ peak power of ~23.7 W·kg-1 TUG showed a progressive decrease. The CMJ take-off velocity (Voff) in the normal condition was lower in old than young participants (p<0.001). However, the Voff vs. body weight/MVC relationship of the normal, loaded and unloaded data combined was similar in the old and young participants and fitted the Hill equation (R2 = 0.396). This indicates that 1) only when peak power drops below a critical threshold TUG becomes impaired and 2) there was no evidence for intrinsic slowing of the muscle contractile properties in older people, but rather the older people were working on a slower part of the force-velocity relationship due to weaker muscles.Hans DegensJulia AttiasDaniel EvansFrederick WilkinsEmma Hodson-TolePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0253531 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hans Degens Julia Attias Daniel Evans Frederick Wilkins Emma Hodson-Tole The mobility limitation in healthy older people is due to weakness and not slower muscle contractile properties.
description	The maximal power generating capacity of a muscle declines with age and has a negative impact on the performance of daily life activities. As muscle power is the product of force and velocity, we recruited 20 young (10 men, 10 women: 20-31 years) and 20 older (10 men, 10 women: 65-86 years) people to investigate which of these components contributes to the lower power and performance in old age. After determination of the maximal isometric knee extension torque (MVC), they performed a countermovement jump (CMJ) in 1) the normal situation (normal), 2) with an extra load of 15% body weight (loaded) and 3) 15% lower body weight (unloaded with a pulley system), and a timed up-and-go test (TUG) in the normal or loaded condition. The TUG and CMJ performance was lower in old than young participants (p<0.001). Below a critical CMJ peak power of ~23.7 W·kg-1 TUG showed a progressive decrease. The CMJ take-off velocity (Voff) in the normal condition was lower in old than young participants (p<0.001). However, the Voff vs. body weight/MVC relationship of the normal, loaded and unloaded data combined was similar in the old and young participants and fitted the Hill equation (R2 = 0.396). This indicates that 1) only when peak power drops below a critical threshold TUG becomes impaired and 2) there was no evidence for intrinsic slowing of the muscle contractile properties in older people, but rather the older people were working on a slower part of the force-velocity relationship due to weaker muscles.
format	article
author	Hans Degens Julia Attias Daniel Evans Frederick Wilkins Emma Hodson-Tole
author_facet	Hans Degens Julia Attias Daniel Evans Frederick Wilkins Emma Hodson-Tole
author_sort	Hans Degens
title	The mobility limitation in healthy older people is due to weakness and not slower muscle contractile properties.
title_short	The mobility limitation in healthy older people is due to weakness and not slower muscle contractile properties.
title_full	The mobility limitation in healthy older people is due to weakness and not slower muscle contractile properties.
title_fullStr	The mobility limitation in healthy older people is due to weakness and not slower muscle contractile properties.
title_full_unstemmed	The mobility limitation in healthy older people is due to weakness and not slower muscle contractile properties.
title_sort	mobility limitation in healthy older people is due to weakness and not slower muscle contractile properties.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/cd88beaadb1740d288cd0568621c6ab5
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The mobility limitation in healthy older people is due to weakness and not slower muscle contractile properties.

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