Metabolic and Bactericidal Effects of Targeted Suppression of NadD and NadE Enzymes in Mycobacteria
ABSTRACT Mycobacterium tuberculosis remains a major cause of death due to the lack of treatment accessibility, HIV coinfection, and drug resistance. Development of new drugs targeting previously unexplored pathways is essential to shorten treatment time and eliminate persistent M. tuberculosis. A pr...
Saved in:
Main Authors: | Irina A. Rodionova, Brian M. Schuster, Kristine M. Guinn, Leonardo Sorci, David A. Scott, Xiaoqing Li, Indu Kheterpal, Carolyn Shoen, Michael Cynamon, Christopher Locher, Eric J. Rubin, Andrei L. Osterman |
---|---|
Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2014
|
Subjects: | |
Online Access: | https://doaj.org/article/cd928a37779048cf85d827e12f5c4f8d |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
NAD-seq for profiling the NAD+ capped transcriptome of Arabidopsis thaliana
by: Xiang Yu, et al.
Published: (2021) -
NAD+ loss, a new player in AhR biology: prevention of thymus atrophy and hepatosteatosis by NAD+ repletion
by: Silvia Diani-Moore, et al.
Published: (2017) -
NAD Modulates DNA Methylation and Cell Differentiation
by: Simone Ummarino, et al.
Published: (2021) -
Rozważania nad koncepcją historii językoznawstwa polskiego
by: Władysław T. Miodunka
Published: (2020) -
Effect of NAD+ boosting on kidney ischemia-reperfusion injury.
by: Marya Morevati, et al.
Published: (2021)