Radial keratotomy associated endothelial degeneration

Majid Moshirfar, Andrew Ollerton, Rodmehr T Semnani, Maylon HsuJohn A Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USAPurpose: To describe the presentation and clinical course of eyes with a history of radial keratotomy (RK) and varying d...

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Autores principales:	Moshirfar M, Ollerton A, Semnani RT, Hsu M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/cd95ef36d6d44dee81e78b5e81745403
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spelling	oai:doaj.org-article:cd95ef36d6d44dee81e78b5e817454032021-12-02T05:50:57ZRadial keratotomy associated endothelial degeneration1177-54671177-5483https://doaj.org/article/cd95ef36d6d44dee81e78b5e817454032012-02-01T00:00:00Zhttp://www.dovepress.com/radial-keratotomy-associated-endothelial-degeneration-a9199https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Majid Moshirfar, Andrew Ollerton, Rodmehr T Semnani, Maylon HsuJohn A Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USAPurpose: To describe the presentation and clinical course of eyes with a history of radial keratotomy (RK) and varying degrees of endothelial degeneration.Methods: Retrospective case series were used.Results: Thirteen eyes (seven patients) were identified with clinical findings of significant guttata and a prior history of RK. The mean age of presentation for cornea evaluation was 54.3 years (range: 38&ndash;72 years), averaging 18.7 years (range: 11&ndash;33 years) after RK. The presentation of guttata varied in degree from moderate to severe. Best corrected visual acuity (BCVA) ranged from 20/25 to 20/80. All patients had a history of bilateral RK, except one patient who did not develop any guttata in the eye without prior RK. No patients reported a family history of Fuch&rsquo;s Dystrophy. One patient underwent a penetrating keratoplasty in one eye and a Descemet&rsquo;s stripping automated endothelial keratoplasty (DSAEK) in the other eye.Conclusions: RK may induce a spectrum of endothelial degeneration. In elderly patients, the findings of guttata may signify comorbid Fuch&rsquo;s dystrophy in which RK incisions could potentially hasten endothelial decomposition. In these select patients with stable cornea topography and prior RK, DSAEK may successfully treat RK endothelial degeneration.Keywords: radial keratotomy, RK, Descemet&rsquo;s stripping automated endothelial keratoplasty, DSAEK, guttata, endothelial degeneration, Fuch&rsquo;s dystrophyMoshirfar MOllerton ASemnani RTHsu MDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 213-218 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Moshirfar M Ollerton A Semnani RT Hsu M Radial keratotomy associated endothelial degeneration
description	Majid Moshirfar, Andrew Ollerton, Rodmehr T Semnani, Maylon HsuJohn A Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USAPurpose: To describe the presentation and clinical course of eyes with a history of radial keratotomy (RK) and varying degrees of endothelial degeneration.Methods: Retrospective case series were used.Results: Thirteen eyes (seven patients) were identified with clinical findings of significant guttata and a prior history of RK. The mean age of presentation for cornea evaluation was 54.3 years (range: 38&ndash;72 years), averaging 18.7 years (range: 11&ndash;33 years) after RK. The presentation of guttata varied in degree from moderate to severe. Best corrected visual acuity (BCVA) ranged from 20/25 to 20/80. All patients had a history of bilateral RK, except one patient who did not develop any guttata in the eye without prior RK. No patients reported a family history of Fuch&rsquo;s Dystrophy. One patient underwent a penetrating keratoplasty in one eye and a Descemet&rsquo;s stripping automated endothelial keratoplasty (DSAEK) in the other eye.Conclusions: RK may induce a spectrum of endothelial degeneration. In elderly patients, the findings of guttata may signify comorbid Fuch&rsquo;s dystrophy in which RK incisions could potentially hasten endothelial decomposition. In these select patients with stable cornea topography and prior RK, DSAEK may successfully treat RK endothelial degeneration.Keywords: radial keratotomy, RK, Descemet&rsquo;s stripping automated endothelial keratoplasty, DSAEK, guttata, endothelial degeneration, Fuch&rsquo;s dystrophy
format	article
author	Moshirfar M Ollerton A Semnani RT Hsu M
author_facet	Moshirfar M Ollerton A Semnani RT Hsu M
author_sort	Moshirfar M
title	Radial keratotomy associated endothelial degeneration
title_short	Radial keratotomy associated endothelial degeneration
title_full	Radial keratotomy associated endothelial degeneration
title_fullStr	Radial keratotomy associated endothelial degeneration
title_full_unstemmed	Radial keratotomy associated endothelial degeneration
title_sort	radial keratotomy associated endothelial degeneration
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/cd95ef36d6d44dee81e78b5e81745403
work_keys_str_mv	AT moshirfarm radialkeratotomyassociatedendothelialdegeneration AT ollertona radialkeratotomyassociatedendothelialdegeneration AT semnanirt radialkeratotomyassociatedendothelialdegeneration AT hsum radialkeratotomyassociatedendothelialdegeneration
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Radial keratotomy associated endothelial degeneration

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