Real-time monitoring of single ZTP riboswitches reveals a complex and kinetically controlled decision landscape
Many RNAs become functional before their synthesis completes. Here the authors employ a single-molecule vectorial folding assay mimicking RNA transcription and show that the ZTP riboswitch is kinetically controlled and activated by slower unwinding and strategic pausing.
Enregistré dans:
| Auteurs principaux: | , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2020
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/cd9a444440f54f6dbaa2b5c8d83e460c |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|