Simple method for detecting idiopathic interstitial pneumonias by measuring vertical lung length on chest X-ray

Abstract Detection of idiopathic interstitial pneumonias (IIPs) on chest X-ray is difficult for non-specialist physicians, especially in patients with mild IIPs. The current study aimed to evaluate the usefulness of a simple method for detecting IIPs by measuring vertical lung length (VLL) in chest...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Masato Karayama, Yoichiro Aoshima, Hideki Yasui, Hironao Hozumi, Yuzo Suzuki, Kazuki Furuhashi, Tomoyuki Fujisawa, Noriyuki Enomoto, Yutaro Nakamura, Naoki Inui, Takafumi Suda
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/cda305b8e1ae4f9ca1e02dee73ed0dce
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:cda305b8e1ae4f9ca1e02dee73ed0dce
record_format	dspace
spelling	oai:doaj.org-article:cda305b8e1ae4f9ca1e02dee73ed0dce2021-12-02T14:26:07ZSimple method for detecting idiopathic interstitial pneumonias by measuring vertical lung length on chest X-ray10.1038/s41598-021-87452-z2045-2322https://doaj.org/article/cda305b8e1ae4f9ca1e02dee73ed0dce2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-87452-zhttps://doaj.org/toc/2045-2322Abstract Detection of idiopathic interstitial pneumonias (IIPs) on chest X-ray is difficult for non-specialist physicians, especially in patients with mild IIPs. The current study aimed to evaluate the usefulness of a simple method for detecting IIPs by measuring vertical lung length (VLL) in chest X-rays to quantify decreased lung volume. A total of 280 consecutive patients with IIPs were randomly allocated to exploratory and validation cohorts, and 140 controls were selected for each cohort by propensity score-matching. Upper (uVLL; from apex to tracheal carina), lower (lVLL; from carina to costophrenic angle), and total VLL (tVLL; from apex to costophrenic angle), and the l/uVLL ratio were measured on chest X-rays. Patients in the exploratory cohort had significantly decreased uVLL, lVLL, tVLL, and l/uVLL ratio compared with controls (all p < 0.001). Receiver operating characteristic curve analyses demonstrated that lVLL (area under the curve [AUC] 0.86, sensitivity 0.65, specificity 0.92), tVLL (AUC 0.83, sensitivity 0.75, specificity 0.80), and l/uVLL ratio (AUC 0.80, sensitivity 0.72, specificity 0.79) had high diagnostic accuracies for IIPs. These results were reproduced in the validation cohort. IIP patients thus have decreased VLLs, and measurements of VLL may thus aid the accurate detection of IIPs.Masato KarayamaYoichiro AoshimaHideki YasuiHironao HozumiYuzo SuzukiKazuki FuruhashiTomoyuki FujisawaNoriyuki EnomotoYutaro NakamuraNaoki InuiTakafumi SudaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Masato Karayama Yoichiro Aoshima Hideki Yasui Hironao Hozumi Yuzo Suzuki Kazuki Furuhashi Tomoyuki Fujisawa Noriyuki Enomoto Yutaro Nakamura Naoki Inui Takafumi Suda Simple method for detecting idiopathic interstitial pneumonias by measuring vertical lung length on chest X-ray
description	Abstract Detection of idiopathic interstitial pneumonias (IIPs) on chest X-ray is difficult for non-specialist physicians, especially in patients with mild IIPs. The current study aimed to evaluate the usefulness of a simple method for detecting IIPs by measuring vertical lung length (VLL) in chest X-rays to quantify decreased lung volume. A total of 280 consecutive patients with IIPs were randomly allocated to exploratory and validation cohorts, and 140 controls were selected for each cohort by propensity score-matching. Upper (uVLL; from apex to tracheal carina), lower (lVLL; from carina to costophrenic angle), and total VLL (tVLL; from apex to costophrenic angle), and the l/uVLL ratio were measured on chest X-rays. Patients in the exploratory cohort had significantly decreased uVLL, lVLL, tVLL, and l/uVLL ratio compared with controls (all p < 0.001). Receiver operating characteristic curve analyses demonstrated that lVLL (area under the curve [AUC] 0.86, sensitivity 0.65, specificity 0.92), tVLL (AUC 0.83, sensitivity 0.75, specificity 0.80), and l/uVLL ratio (AUC 0.80, sensitivity 0.72, specificity 0.79) had high diagnostic accuracies for IIPs. These results were reproduced in the validation cohort. IIP patients thus have decreased VLLs, and measurements of VLL may thus aid the accurate detection of IIPs.
format	article
author	Masato Karayama Yoichiro Aoshima Hideki Yasui Hironao Hozumi Yuzo Suzuki Kazuki Furuhashi Tomoyuki Fujisawa Noriyuki Enomoto Yutaro Nakamura Naoki Inui Takafumi Suda
author_facet	Masato Karayama Yoichiro Aoshima Hideki Yasui Hironao Hozumi Yuzo Suzuki Kazuki Furuhashi Tomoyuki Fujisawa Noriyuki Enomoto Yutaro Nakamura Naoki Inui Takafumi Suda
author_sort	Masato Karayama
title	Simple method for detecting idiopathic interstitial pneumonias by measuring vertical lung length on chest X-ray
title_short	Simple method for detecting idiopathic interstitial pneumonias by measuring vertical lung length on chest X-ray
title_full	Simple method for detecting idiopathic interstitial pneumonias by measuring vertical lung length on chest X-ray
title_fullStr	Simple method for detecting idiopathic interstitial pneumonias by measuring vertical lung length on chest X-ray
title_full_unstemmed	Simple method for detecting idiopathic interstitial pneumonias by measuring vertical lung length on chest X-ray
title_sort	simple method for detecting idiopathic interstitial pneumonias by measuring vertical lung length on chest x-ray
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/cda305b8e1ae4f9ca1e02dee73ed0dce
work_keys_str_mv	AT masatokarayama simplemethodfordetectingidiopathicinterstitialpneumoniasbymeasuringverticallunglengthonchestxray AT yoichiroaoshima simplemethodfordetectingidiopathicinterstitialpneumoniasbymeasuringverticallunglengthonchestxray AT hidekiyasui simplemethodfordetectingidiopathicinterstitialpneumoniasbymeasuringverticallunglengthonchestxray AT hironaohozumi simplemethodfordetectingidiopathicinterstitialpneumoniasbymeasuringverticallunglengthonchestxray AT yuzosuzuki simplemethodfordetectingidiopathicinterstitialpneumoniasbymeasuringverticallunglengthonchestxray AT kazukifuruhashi simplemethodfordetectingidiopathicinterstitialpneumoniasbymeasuringverticallunglengthonchestxray AT tomoyukifujisawa simplemethodfordetectingidiopathicinterstitialpneumoniasbymeasuringverticallunglengthonchestxray AT noriyukienomoto simplemethodfordetectingidiopathicinterstitialpneumoniasbymeasuringverticallunglengthonchestxray AT yutaronakamura simplemethodfordetectingidiopathicinterstitialpneumoniasbymeasuringverticallunglengthonchestxray AT naokiinui simplemethodfordetectingidiopathicinterstitialpneumoniasbymeasuringverticallunglengthonchestxray AT takafumisuda simplemethodfordetectingidiopathicinterstitialpneumoniasbymeasuringverticallunglengthonchestxray
_version_	1718391396419764224

Simple method for detecting idiopathic interstitial pneumonias by measuring vertical lung length on chest X-ray

Ejemplares similares