A H2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging

A H2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging

Fluorescent imaging in the second biological window has advantages for in vivo applications. Here, the authors synthesise a molecular nanoprobe which activates upon binding H2O2, generating both strong fluorescent NIR-II emission and ultrasound signal for multi-mode imaging of inflammatory diseases.

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Autores principales: Junjie Chen, Longqi Chen, Yinglong Wu, Yichang Fang, Fang Zeng, Shuizhu Wu, Yanli Zhao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/cdb0409e99074e75aa745ac50ef797a3
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spelling oai:doaj.org-article:cdb0409e99074e75aa745ac50ef797a32021-11-28T12:31:56ZA H2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging10.1038/s41467-021-27233-42041-1723https://doaj.org/article/cdb0409e99074e75aa745ac50ef797a32021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27233-4https://doaj.org/toc/2041-1723Fluorescent imaging in the second biological window has advantages for in vivo applications. Here, the authors synthesise a molecular nanoprobe which activates upon binding H2O2, generating both strong fluorescent NIR-II emission and ultrasound signal for multi-mode imaging of inflammatory diseases.Junjie ChenLongqi ChenYinglong WuYichang FangFang ZengShuizhu WuYanli ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Junjie Chen
Longqi Chen
Yinglong Wu
Yichang Fang
Fang Zeng
Shuizhu Wu
Yanli Zhao
A H2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging
description Fluorescent imaging in the second biological window has advantages for in vivo applications. Here, the authors synthesise a molecular nanoprobe which activates upon binding H2O2, generating both strong fluorescent NIR-II emission and ultrasound signal for multi-mode imaging of inflammatory diseases.
format article
author Junjie Chen
Longqi Chen
Yinglong Wu
Yichang Fang
Fang Zeng
Shuizhu Wu
Yanli Zhao
author_facet Junjie Chen
Longqi Chen
Yinglong Wu
Yichang Fang
Fang Zeng
Shuizhu Wu
Yanli Zhao
author_sort Junjie Chen
title A H2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging
title_short A H2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging
title_full A H2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging
title_fullStr A H2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging
title_full_unstemmed A H2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging
title_sort h2o2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and nir-ii fluorescent imaging
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/cdb0409e99074e75aa745ac50ef797a3
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