Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success

The transcription factor FOXA2 is specifically expressed in uterine glands. Here, using two conditional FOXA2 knockout mouse models, the authors show that glandular epithelia of the endometrium are required for timely embryo implantation and subsequent endometrial decidualization during successful p...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Andrew M. Kelleher, Jessica Milano-Foster, Susanta K. Behura, Thomas E. Spencer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/cdb4aecdb05a4e399460b8626a609838
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:cdb4aecdb05a4e399460b8626a609838
record_format dspace
spelling oai:doaj.org-article:cdb4aecdb05a4e399460b8626a6098382021-12-02T14:41:28ZUterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success10.1038/s41467-018-04848-82041-1723https://doaj.org/article/cdb4aecdb05a4e399460b8626a6098382018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04848-8https://doaj.org/toc/2041-1723The transcription factor FOXA2 is specifically expressed in uterine glands. Here, using two conditional FOXA2 knockout mouse models, the authors show that glandular epithelia of the endometrium are required for timely embryo implantation and subsequent endometrial decidualization during successful pregnancy establishment.Andrew M. KelleherJessica Milano-FosterSusanta K. BehuraThomas E. SpencerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Andrew M. Kelleher
Jessica Milano-Foster
Susanta K. Behura
Thomas E. Spencer
Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success
description The transcription factor FOXA2 is specifically expressed in uterine glands. Here, using two conditional FOXA2 knockout mouse models, the authors show that glandular epithelia of the endometrium are required for timely embryo implantation and subsequent endometrial decidualization during successful pregnancy establishment.
format article
author Andrew M. Kelleher
Jessica Milano-Foster
Susanta K. Behura
Thomas E. Spencer
author_facet Andrew M. Kelleher
Jessica Milano-Foster
Susanta K. Behura
Thomas E. Spencer
author_sort Andrew M. Kelleher
title Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success
title_short Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success
title_full Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success
title_fullStr Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success
title_full_unstemmed Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success
title_sort uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/cdb4aecdb05a4e399460b8626a609838
work_keys_str_mv AT andrewmkelleher uterineglandscoordinateontimeembryoimplantationandimpactendometrialdecidualizationforpregnancysuccess
AT jessicamilanofoster uterineglandscoordinateontimeembryoimplantationandimpactendometrialdecidualizationforpregnancysuccess
AT susantakbehura uterineglandscoordinateontimeembryoimplantationandimpactendometrialdecidualizationforpregnancysuccess
AT thomasespencer uterineglandscoordinateontimeembryoimplantationandimpactendometrialdecidualizationforpregnancysuccess
_version_ 1718389899619467264