EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia

Sensory hair cells develop an asymmetric architecture to restrict stimulus detection to a single axis. Here the authors identify GPR156 as directing a 180-degree reversal in hair cell orientation through Gαi, downstream of EMX2 in the mouse inner ear and zebrafish lateral line.

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Autores principales:	Katie S. Kindt, Anil Akturk, Amandine Jarysta, Matthew Day, Alisha Beirl, Michaela Flonard, Basile Tarchini
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cdb53b6108644c36ae6b163b74f2d635
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spelling	oai:doaj.org-article:cdb53b6108644c36ae6b163b74f2d6352021-12-02T14:58:44ZEMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia10.1038/s41467-021-22997-12041-1723https://doaj.org/article/cdb53b6108644c36ae6b163b74f2d6352021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22997-1https://doaj.org/toc/2041-1723Sensory hair cells develop an asymmetric architecture to restrict stimulus detection to a single axis. Here the authors identify GPR156 as directing a 180-degree reversal in hair cell orientation through Gαi, downstream of EMX2 in the mouse inner ear and zebrafish lateral line.Katie S. KindtAnil AkturkAmandine JarystaMatthew DayAlisha BeirlMichaela FlonardBasile TarchiniNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Katie S. Kindt Anil Akturk Amandine Jarysta Matthew Day Alisha Beirl Michaela Flonard Basile Tarchini EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia
description	Sensory hair cells develop an asymmetric architecture to restrict stimulus detection to a single axis. Here the authors identify GPR156 as directing a 180-degree reversal in hair cell orientation through Gαi, downstream of EMX2 in the mouse inner ear and zebrafish lateral line.
format	article
author	Katie S. Kindt Anil Akturk Amandine Jarysta Matthew Day Alisha Beirl Michaela Flonard Basile Tarchini
author_facet	Katie S. Kindt Anil Akturk Amandine Jarysta Matthew Day Alisha Beirl Michaela Flonard Basile Tarchini
author_sort	Katie S. Kindt
title	EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia
title_short	EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia
title_full	EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia
title_fullStr	EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia
title_full_unstemmed	EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia
title_sort	emx2-gpr156-gαi reverses hair cell orientation in mechanosensory epithelia
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/cdb53b6108644c36ae6b163b74f2d635
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EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia

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