Optical imaging of metabolic dynamics in animals

Non-destructive methods to image metabolism in situ in living tissues are limited. Here the authors combine deuterium oxide probing and stimulated Raman scattering microscopy to image lipid metabolic dynamics and protein synthesis in cells and in vivo in mice, C. elegans, and zebrafish.

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Detalles Bibliográficos
Autores principales:	Lingyan Shi, Chaogu Zheng, Yihui Shen, Zhixing Chen, Edilson S. Silveira, Luyuan Zhang, Mian Wei, Chang Liu, Carmen de Sena-Tomas, Kimara Targoff, Wei Min
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cdb87769bb72441c87752a122bb3677f
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spelling	oai:doaj.org-article:cdb87769bb72441c87752a122bb3677f2021-12-02T16:49:33ZOptical imaging of metabolic dynamics in animals10.1038/s41467-018-05401-32041-1723https://doaj.org/article/cdb87769bb72441c87752a122bb3677f2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05401-3https://doaj.org/toc/2041-1723Non-destructive methods to image metabolism in situ in living tissues are limited. Here the authors combine deuterium oxide probing and stimulated Raman scattering microscopy to image lipid metabolic dynamics and protein synthesis in cells and in vivo in mice, C. elegans, and zebrafish.Lingyan ShiChaogu ZhengYihui ShenZhixing ChenEdilson S. SilveiraLuyuan ZhangMian WeiChang LiuCarmen de Sena-TomasKimara TargoffWei MinNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lingyan Shi Chaogu Zheng Yihui Shen Zhixing Chen Edilson S. Silveira Luyuan Zhang Mian Wei Chang Liu Carmen de Sena-Tomas Kimara Targoff Wei Min Optical imaging of metabolic dynamics in animals
description	Non-destructive methods to image metabolism in situ in living tissues are limited. Here the authors combine deuterium oxide probing and stimulated Raman scattering microscopy to image lipid metabolic dynamics and protein synthesis in cells and in vivo in mice, C. elegans, and zebrafish.
format	article
author	Lingyan Shi Chaogu Zheng Yihui Shen Zhixing Chen Edilson S. Silveira Luyuan Zhang Mian Wei Chang Liu Carmen de Sena-Tomas Kimara Targoff Wei Min
author_facet	Lingyan Shi Chaogu Zheng Yihui Shen Zhixing Chen Edilson S. Silveira Luyuan Zhang Mian Wei Chang Liu Carmen de Sena-Tomas Kimara Targoff Wei Min
author_sort	Lingyan Shi
title	Optical imaging of metabolic dynamics in animals
title_short	Optical imaging of metabolic dynamics in animals
title_full	Optical imaging of metabolic dynamics in animals
title_fullStr	Optical imaging of metabolic dynamics in animals
title_full_unstemmed	Optical imaging of metabolic dynamics in animals
title_sort	optical imaging of metabolic dynamics in animals
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/cdb87769bb72441c87752a122bb3677f
work_keys_str_mv	AT lingyanshi opticalimagingofmetabolicdynamicsinanimals AT chaoguzheng opticalimagingofmetabolicdynamicsinanimals AT yihuishen opticalimagingofmetabolicdynamicsinanimals AT zhixingchen opticalimagingofmetabolicdynamicsinanimals AT edilsonssilveira opticalimagingofmetabolicdynamicsinanimals AT luyuanzhang opticalimagingofmetabolicdynamicsinanimals AT mianwei opticalimagingofmetabolicdynamicsinanimals AT changliu opticalimagingofmetabolicdynamicsinanimals AT carmendesenatomas opticalimagingofmetabolicdynamicsinanimals AT kimaratargoff opticalimagingofmetabolicdynamicsinanimals AT weimin opticalimagingofmetabolicdynamicsinanimals
_version_	1718383303456718848

Optical imaging of metabolic dynamics in animals

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