The Symmetrical Wave Pattern of Base-Pair Substitution Rates across the <named-content content-type="genus-species">Escherichia coli</named-content> Chromosome Has Multiple Causes

ABSTRACT Mutation accumulation experiments followed by whole-genome sequencing have revealed that, for several bacterial species, the rate of base-pair substitutions (BPSs) is not constant across the chromosome but varies in a wave-like pattern that is symmetrical about the origin of replication. Th...

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Bibliographic Details
Main Authors: Brittany A. Niccum, Heewook Lee, Wazim MohammedIsmail, Haixu Tang, Patricia L. Foster
Format: article
Language:EN
Published: American Society for Microbiology 2019
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Online Access:https://doaj.org/article/cdc38ff6c16e4628ad3d167ba17abdb4
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