Use of CRISPR-Cas9 To Target Homologous Recombination Limits Transformation-Induced Genomic Changes in <named-content content-type="genus-species">Candida albicans</named-content>
ABSTRACT Most of our knowledge relating to molecular mechanisms of human fungal pathogenesis in Candida albicans relies on reverse genetics approaches, requiring strain engineering. DNA-mediated transformation of C. albicans has been described as highly mutagenic, potentially accentuated by the orga...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
American Society for Microbiology
2020
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/cdc40270ef2740f2a5459b3e3b97d217 |
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