Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization

The generation of vasculature in organs is regulated by cross-talk between the developing tissue and specialized endothelial cells. Here, the authors show that vessel growth feeding the zebrafish spinal cord is coordinated by balancing neuron-derived pro-angiogenic ligand Vegfaa and its receptor, sF...

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Bibliographic Details
Main Authors: Raphael Wild, Alina Klems, Masanari Takamiya, Yuya Hayashi, Uwe Strähle, Koji Ando, Naoki Mochizuki, Andreas van Impel, Stefan Schulte-Merker, Janna Krueger, Laetitia Preau, Ferdinand le Noble
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/cdc7bf090b8e4a769873ee7f421be5b1
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